Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
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Fen<strong>of</strong>ibrate & Adiponectin in Patients<br />
with Hypertriglyceridemia<br />
Adiponectin Levels (ug/ml)<br />
15<br />
10<br />
5<br />
Adiponectin (ug/ml)<br />
P = 0.008<br />
CONCLUSIONS: Fen<strong>of</strong>ibrate<br />
therapy significantly improved percent<br />
flow-mediated dilator response to<br />
hyperemia, reduced inflammation<br />
marker levels, increased adiponectin<br />
levels, and improved insulin<br />
sensitivity in hypertriglyceridemic or<br />
metabolic syndrome patients.<br />
0<br />
Placebo<br />
Fen<strong>of</strong>ibrate<br />
Koh, KK et al. Diabetes Care 2005;28:1419-24
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