Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
Fibrate Mechanism of Action - The Center for Cholesterol Management
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Veterans Affairs HDL Intervention Trial (VA-HIT)<br />
Explaining the Beneficial Effect <strong>of</strong> Gemfibrozil<br />
Conclusions:<br />
<strong>The</strong> effects <strong>of</strong> gemfibrozil on NMR-measured<br />
LDL and HDL particle subclasses, which are not<br />
reflected by conventional lipoprotein cholesterol<br />
measures, help to explain the demonstrated<br />
benefit <strong>of</strong> fibrate therapy in patients with<br />
low HDL cholesterol.<br />
Otvos J et al Circulation 2006:113 on line
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