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REVIEW QUESTIONS AND EXERCISES 583
Infants Children Adults
W (kg) V (liters) W (kg) V (liters) W (kg) V (liters)
10.3 4.068 37 14.40
10.6 3.640 28 10.90
10.7 4.067 47 15.40
10.8 8.366 29 9.86
11.0 4.614 37 14.40
12.5 3.168
13.1 4.158
Source: Dr. Klaus Stoeckel. Used with permission.
24. According to Fils-Aime et al. (A-21), epidemiologic surveys have found that alcoholism is the most
common mental or substance abuse disorder among men in the United States. Fils-Aime and associates
investigated the interrelationships of age at onset of excessive alcohol consumption, family history
of alcoholism, psychiatric comorbidity, and cerebrospinal fluid (CSF) monoamine metabolite
concentrations in abstinent, treatment-seeking alcoholics. Subjects were mostly white males classified
as experiencing early (25 years or younger) or late (older than 25 years) onset of excessive alcohol
consumption. Among the data collected were the following measurements on CSF tryptophan
(TRYPT) and 5-hydroxyindoleacetic acid (5-HIAA) concentrations (pmol/ml).
Onset
Onset
1 Early 1 Early
5-HIAA TRYPT 0 Late 5-HIAA TRYPT 0 Late
57 3315 1 102 3181 1
116 2599 0 51 2513 1
81 3334 1 92 2764 1
78 2505 0 104 3098 1
206 3269 0 50 2900 1
64 3543 1 93 4125 1
123 3374 0 146 6081 1
147 2345 1 96 2972 1
102 2855 1 112 3962 0
93 2972 1 23 4894 1
128 3904 0 109 3543 1
69 2564 1 80 2622 1
20 8832 1 111 3012 1
66 4894 0 85 2685 1
90 6017 1 131 3059 0
103 3143 0 58 3946 1
68 3729 0 110 3356 0
81 3150 1 80 3671 1
143 3955 1 42 4155 1
121 4288 1 80 1923 1
149 3404 0 91 3589 1
82 2547 1 102 3839 0
(Continued)