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662 CHAPTER 12 THE CHI-SQUARE DISTRIBUTION AND THE ANALYSIS OF FREQUENCIES<br />

Total Total Total<br />

Duration of Duration of Duration of<br />

Remission Remission Remission Remission Remission Remission<br />

(Months) Status a (Months) Status a (Months) Status a<br />

3 1 8 2 26 1<br />

3 2 9 2 27 1<br />

3 1 10 1 28 2<br />

3 1 10 1 29 1<br />

3 1 11 2 31 2<br />

4 1 13 1 31 1<br />

4 1 16 1 33 2<br />

4 1 16 2 39 2<br />

5 1 17 2 41 1<br />

5 1 18 2 44 1<br />

5 1 20 1 46 1<br />

5 1 22 1 46 2<br />

5 1 22 2 48 1<br />

5 1 22 2 48 2<br />

5 1 23 1 48 1<br />

6 1 24 2 49 1<br />

6 1 25 2 50 1<br />

6 1 25 2 53 1<br />

7 1 26 1 70 2<br />

8 2 26 1 94 1<br />

8 1<br />

8 2<br />

a 1 yes (the patient is still in remission); 2 no (the patient has relapsed).<br />

Source: Dr. Mary Ann Banerji. Used with permission.<br />

12.8.3 If available in your library, read the article, “Impact of Obesity on Allogeneic Stem Cell Transplant<br />

Patients: A Matched Case-Controlled Study,” by Donald R. Fleming et al. [American Journal of<br />

Medicine, 102 (1997), 265–268] and answer the following questions:<br />

(a) How was survival time determined<br />

(b) Why do you think the authors used the Wilcoxon test (Breslow test) for comparing the survival<br />

curves<br />

(c) Explain the meaning of the p values reported for Figures 1 through 4.<br />

(d) What specific statistical results allow the authors to arrive at their stated conclusion<br />

12.8.4 If available in your library, read the article, “Improved Survival in Patients with Locally Advanced<br />

Prostate Cancer Treated with Radiotherapy and Goserelin,” by Michel Bolla et al. [New England<br />

Journal of Medicine, 337 (1997), 295–300], and answer the following questions:<br />

(a) How was survival time determined<br />

(b) Why do you think the authors used the log-rank test for comparing the survival curves

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