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Disease staging: CliniCal anD CoDeD Criteria - HCUP

Disease staging: CliniCal anD CoDeD Criteria - HCUP

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Clinical <strong>Criteria</strong> with Description, Diagnostic Findings and ICD-9-CM codes<br />

DXCat Number: HEM07<br />

MultiStage: No<br />

DXCat Label: Anemia: Thalassemia Specificity: A<br />

Etiology: Genetic (or hereditary)<br />

Stage Description Diagnostic findings ICD-9-CM Codes<br />

1.01 Alpha thalassemia trait Microcytosis:<br />

DX 2824, 28249;<br />

AND anemia:<br />

AND serum iron > 55 ug/dl in males or > 35 ug/dl in females [chemistry report]<br />

AND total iron binding capacity < 513 ug/dl [chemistry report]<br />

OR serum ferritin > 12 ng/ml [chemistry report]<br />

OR normal iron stores [bone marrow biopsy report]<br />

OR hemoglobin Barts 5-10% in newborn [hemoglobin electrophoresis report]<br />

1.02 Beta thalassemia trait or thalassemia minor Microcytosis:<br />

AND anemia:<br />

AND hemoglobin A2 > 3% [hemoglobin electrophoresis report]<br />

2.01 Hemoglobin H disease (alpha thalassemia<br />

intermedia)<br />

Microcytosis:<br />

AND anemia:<br />

AND hemoglobin H 4-20% in child or adult [hemoglobin electrophoresis report]<br />

OR hemoglobin Barts 5-10% in newborn [hemoglobin electrophoresis report]<br />

2.02 Beta thalassemia intermedia Microcytosis:<br />

AND hemoglobin 6-8 g/dl [hematology report]<br />

AND hemoglobin A 20-40% [hemoglobin electrophoresis report]<br />

AND hemoglobin F 60-80% [hemoglobin electrophoresis report]<br />

3.01 Beta thalassemia major or Cooley's anemia Hemoglobin F > 90% [hemoglobin electrophoresis report]<br />

AND hemoglobin ≤ 6 gm/dl [complete blood count report]<br />

AND erythroid hyperplasia of the bone marrow [bone marrow report]<br />

AND microcytosis:<br />

AND serum iron > 209 ug/dl [chemistry report]<br />

OR serum ferritin ≥ 370 ng/ml[chemistry report]<br />

OR normal iron stores [bone marrow biopsy report]<br />

AND reticulocyte count ≥ 1.5% of total erythrocytes [complete blood count report]<br />

AND total bilirubin ≥ 3.0 mg/dl [chemistry report]<br />

3.02 with congestive heart failure Stage 2.01-3.01<br />

AND congestive heart failure:<br />

3.03 Homozygous alpha thalassemia with<br />

hydrops fetalis<br />

4.00 with death Stage 2.01-3.03<br />

AND death<br />

Hemoglobin Barts 80-90%; no Hemoglobin A or F in newborn [Hemoglobin electrophoresis report]<br />

AND hydrops fetalis<br />

NO;<br />

NO;<br />

NO;<br />

NO;<br />

STAGE 1.01 + GROUP<br />

CHF__NON_HTN;<br />

STAGE 1.01-3.02 + DX 7780;<br />

NO;<br />

Thursday, January 07, 2010 9:22:03 AM<br />

©2010 Thomson Reuters. All rights reserved.

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