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Disease staging: CliniCal anD CoDeD Criteria - HCUP

Disease staging: CliniCal anD CoDeD Criteria - HCUP

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Congenital adrenal hyperplasia:<br />

Urine 17-ketosteroids > 20 mg/24hr [urine chemistry report]<br />

Reference ranges: 1 - 4 Y < 1 mg/d<br />

5 - 9 y < 3 mg/d<br />

10 - 15 y 1 - 6 mg/d<br />

15 - 16 y Male 3 - 13 mg/d<br />

Female 2 - 8 mg/d<br />

Adult Male 10 - 25 mg/d<br />

Female 6 - 14 mg/d<br />

Due to 21-Hydroxylase deficiency<br />

AND Urinary 17-hydroxyprogesterone increased [urine chemistry report]<br />

OR 11-Beta hydroxylase deficiency<br />

AND Urinary tetrahydro-17-deoxycorticosol increased [urine chemistry<br />

report]<br />

AND Serum 11-deoxycorticosterone increased [urine chemistry report]<br />

AND Serum 11-deoxycortisol increased [urine chemistry report]<br />

OR 3-Beta hydroxysteroid dehydrogenase deficiency [urine chemistry report]<br />

AND Serum dehydroepiandrosterone increased [urine chemistry report]<br />

Congestive heart failure (CHF):<br />

Initial central venous pressure ≥15 cm H 2 O [central venous pressure report or<br />

pulmonary artery catheter report]<br />

OR Initial peak systolic right ventricular pressure ≥ 25 mmHg<br />

OR Initial pulmonary wedge pressure ≥ 18 mmHg<br />

OR Low cardiac output measured by ejection fraction ≤ 50%<br />

[echocardiogram or nuclear ejection fraction report]<br />

OR Cardiac output ≤4 L/min [cardiac catheterization report]<br />

Presumptive Diagnostic Findings:<br />

Jugular venous distention<br />

OR Pedal edema 3+<br />

OR S 3 gallop<br />

OR Bibasilar rales<br />

OR Congestive heart failure [chest x-ray report]<br />

Infants:<br />

Congestive heart failure [chest x-ray report]<br />

AND Tachycardia<br />

AND Tachypnea<br />

AND Rales on auscultation of the lungs<br />

AND Capillary refill > 2 seconds<br />

AND Hepatomegaly<br />

Deleted:<br />

Deleted: OR Hepatojugular reflux<br />

Congestive heart failure (CHF) acute:<br />

CHF and duration < 7 days<br />

G-8

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