Disease staging: CliniCal anD CoDeD Criteria - HCUP

Clinical Criteria with Description, Diagnostic Findings and ICD-9-CM codes
DXCat Number: INF22
MultiStage: No
DXCat Label: Reye's Syndrome Specificity: A
Etiology:
Infection; Toxicologic
Stage Description Diagnostic findings ICD-9-CM Codes
3.01 Reye's syndrome History of recent convalescence from an upper respiratory tract infection, influenza or varicella in
child aged ≤ 16 years old
DX 33181;
OR history of salicylate use
AND disorientation:
OR protacted vomiting
OR lethargy
AND fatty infiltration of the liver [operative or pathology report]
OR serum ammonia > 50 mcg/dL [chemistry report]
AND AST [SGOT] ≥ 105 u/l [chemistry report]
AND ALT [SGPT ] ≥ 90 u/l [chemistry report]
3.02 with hypoglycemia Stage 3.01
AND hypoglycemia:
3.03 with hepatic failure Stage 3.01-3.02
AND hyperammonemia:
3.04 with seizures Stage 3.01-3.03
AND seizures
3.05 with respiratory failure Stage 3.01-3.04
AND respiratory failure:
3.06 with decerebrate rigidity Stage 3.01-3.05
AND decerebrate rigidity
OR cerebral edema and herniation [CT or MRI scan report]
3.07 with coma Stage 3.01-3.06
AND coma:
3.08 with shock Stage 3.01-3.07
AND shock:
4.00 with death Stage 3.01-3.08
AND death
STAGE 3.01 + DXCAT END08;
STAGE 3.01-3.02 + (DX 570 OR
GROUP HYPR_AMMON);
STAGE 3.01-3.03 + DX 78031-
78039;
STAGE 3.01-3.04 + GROUP
RESP_FAIL;
STAGE 3.01-3.05 + DX 3484 + DX
3485;
STAGE 3.01-3.06 + GROUP COMA;
STAGE 3.01-3.07 + (GROUP
SHOCKC OR GROUP SHOCKN) ;
NO;
References:
Balisteri WF. Reye's syndrome. In: Behrman RE, Kliegman RM, Arvin AM, Nelson WE, eds. Nelson Textbook of Pediatrics. 15th ed. Philadelphia, PA: WB Saunders; 1996:1144-
1145.
Glasgow JFT and Moore R. Current concepts in Reye's syndrome. Brit. J. Hosp. Med. 1993;50:599-604.
Greene CL, Blitzer MG, Shapira E. Inborn errors of metabolism and Reye's syndrome: differential diagnosis. J. Pediatrics 1988;113:156-159.
Sokol RJ and Narkewicz MR. Liver and pancreas/Reye's syndrome. In: Hay WW, Groosthius JR, Hayward AR, Levin MJ, eds. Current Pediatric Diagnosis and Treatment. 13th
ed. Stamford, CT: Appleton & Lange; 1997:598-599.
Thursday, January 07, 2010 9:22:26 AM
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