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Disease staging: CliniCal anD CoDeD Criteria - HCUP

Disease staging: CliniCal anD CoDeD Criteria - HCUP

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Hepatitis:<br />

Serum bilirubin > 3 mg/dL [chemistry report]<br />

AND AST > 60 U/L [chemistry report]<br />

OR ALT > 60 U/L [chemistry report]<br />

OR GGT > 38 U/L [chemistry report]<br />

AND Hepatomegaly [physical examination, liver-spleen scan or CT scan]<br />

HIV (Human Immunodeficiency Virus) infection:<br />

Screening: EIA test for antibodies to HIV<br />

Confirmatory: Western blot for HIV antigens<br />

Huntington’s disease (Huntington’s chorea):<br />

Chromosome studies: Repeated CAG sequences in gene IT15<br />

Deleted: Histoplasmosis: <br />

Skin test for delayed hypersensitivity to<br />

Histoplasma<br />

AND Increased complement-fixing<br />

antibodies to Histoplasma <br />

OR Blood and urine cultures positive<br />

(in disseminated form)<br />

Deleted: sequence<br />

5-Hydroxyindoleacetic acid, urine (5-HIAA):<br />

Increased: > 25 mg/d [urine chemistry report]<br />

Reference range: Negative, < 25 mg/d<br />

Hyperaldosteronism:<br />

Increased (Average sodium diet)<br />

Urine aldosterone > 20 μg/d [urine chemistry report]<br />

OR Plasma aldosterone ≥17.4 ng/dL [chemistry report]<br />

Reference ranges:<br />

Depends on sodium intake, age, sex and posture<br />

Urine: Total urinary Na<br />

mEq/d<br />

Urinary aldosterone<br />

μg/d<br />

< 20 35 - 80<br />

50 13 - 33<br />

100 5 - 24<br />

200 1 - 16<br />

Plasma: Adults (Average sodium diet)<br />

Supine 3 - 16 ng/dL<br />

Upright 7 - 30 ng/dL<br />

Hyperammonemia:<br />

Increased: Serum ammonia > 98 ug/dL [chemistry report]<br />

Reference range: 19 - 60 μg/dL<br />

G-17

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