Pharmaceutical Technology: Controlled Drug Release, Volume 2
Pharmaceutical Technology: Controlled Drug Release, Volume 2
Pharmaceutical Technology: Controlled Drug Release, Volume 2
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MULTIPARTICULATES [CH. 10 123<br />
Fig. 4—In vitro release profile of microcapsules (particle size , 540 µm; core:polymer ratio, 1:2): ●. RS 100; ○,<br />
RSPM; ▲, S 100; □, L 100.<br />
3 [] P.A.Mitenko and R.I.Ogilvie, N. Engl., J. Med., 289, 600 (1973).<br />
4 [] D.E.Zaske, K.W.Mitler, E.M.Strem, S.Austrian and P.B.Johnson, J. Am. Med. Assoc., 237, 1453 (1979).<br />
5 [] M.Weinberger, L.Hendles, L.Wong and L.Vaughan, J. Pediatr., 99, 145 (1981).<br />
6 [] S.K.Das and B.K.Gupta, <strong>Drug</strong> Dev. Ind. Pharm., 14, 537 (1988).<br />
7 [] J.Vasiliades and T.Turner, Clin. Chim. Acta, 69, 491 (1976).<br />
Table 3—Pharmacokinetic parameters<br />
Each point represents the average of six results.