Pharmaceutical Technology: Controlled Drug Release, Volume 2
Pharmaceutical Technology: Controlled Drug Release, Volume 2
Pharmaceutical Technology: Controlled Drug Release, Volume 2
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194 INDEX<br />
dry granulation, 43<br />
electrolytes, 21, 155<br />
elimination half life, 117<br />
emulsion base formulation, 91<br />
enteric coated, 33<br />
entrapped air, 32, 37<br />
erosion, 27<br />
ethanol, 27, 87, 95<br />
ethylcellulose, 41, 54, 80, 125<br />
hydrophobic effect, 49<br />
eyes<br />
rabbit, 155<br />
miosis, 161<br />
mydriasis reversion, 161<br />
experimental design, 48, 67<br />
factorial design, 41, 50, 54<br />
Fickian diffusion, 36<br />
film thickness, 76, 145<br />
first-order release, 36, 38, 172<br />
food, 119<br />
fasted, 123<br />
standardized breakfast, 119, 125<br />
friability, 44<br />
gastrointestinal effects, 33, 71, 123<br />
anatomical parts, 127<br />
stomach, colon, 127<br />
gastric emptying, 123<br />
gelatin, 87<br />
gel permeation chromatography, 131<br />
gels, 21, 26, 36<br />
light transmission, 21, 25<br />
ocular, 160<br />
turbidity, 21, 24<br />
gel temperature, 13, 21<br />
goodness of fit, 37<br />
glass transition temperature, 130, 134<br />
glycerol monostearate, 69<br />
glycerol palmitostearate, 32, 80<br />
Hadamard martix, 41, 47<br />
hairless mouse skin, 90, 96<br />
hardness, 32, 37<br />
Heberlein, 33<br />
Schleuniger, 71<br />
Higuchi model, 32, 38, 59, 93, 145<br />
homogeneity, 43<br />
housekeeper wave, 129<br />
hydration rates, 13, 21<br />
hydrophilic matrices, 13, 32, 37<br />
hydroxyethylcellulose (HEC), 13, 183<br />
hydroxypropylcellulose (HPC), 161<br />
hydroxypropylmethylcellulose (HPMC), 13, 21, 69, 80<br />
ibuprofen, 78<br />
implants, 168<br />
bone cement, 171, 176<br />
drug loading, 171, 176<br />
preparation, 172<br />
release kinetics, 171<br />
peptides, 181<br />
silicone matrix, 181<br />
size, 176<br />
ionic strength, 23, 27, 30<br />
in vivo evaluation, 118<br />
indomethacin, 103<br />
interfacial tension, 106<br />
instrumented press, 44<br />
ketoprofen, 69<br />
lactose, 13<br />
lag time, 85, 146<br />
lyotropic series, 24<br />
magnesium stearate, 13, 41, 54, 80<br />
mannitol, 80<br />
manufacturing process, 43<br />
matrix formulations, 13<br />
mechanism of release, 35, 134<br />
mercury porosimetry, 61<br />
methylcellulose, 37, 80<br />
microcapsules, 141<br />
preparation, 141<br />
tablets, 139<br />
microencapsulation, 103<br />
microenvironmental pH, 155<br />
micromatrices, 118<br />
microspheres, 103, 110<br />
minimatrices, 79<br />
monoisopropyl ester of poly(vinyl methyl ether—maleic<br />
anhydride), 155<br />
multiparticulates, 99, 139<br />
pellets, granules, 123<br />
naltrexone, 141