Pharmaceutical Technology: Controlled Drug Release, Volume 2

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MULTIPARTICULATES [CH. 10 123 Fig. 4—In vitro release profile of microcapsules (particle size , 540 µm; core:polymer ratio, 1:2): ●. RS 100; ○, RSPM; ▲, S 100; □, L 100. 3 [] P.A.Mitenko and R.I.Ogilvie, N. Engl., J. Med., 289, 600 (1973). 4 [] D.E.Zaske, K.W.Mitler, E.M.Strem, S.Austrian and P.B.Johnson, J. Am. Med. Assoc., 237, 1453 (1979). 5 [] M.Weinberger, L.Hendles, L.Wong and L.Vaughan, J. Pediatr., 99, 145 (1981). 6 [] S.K.Das and B.K.Gupta, <strong>Drug</strong> Dev. Ind. Pharm., 14, 537 (1988). 7 [] J.Vasiliades and T.Turner, Clin. Chim. Acta, 69, 491 (1976). Table 3—Pharmacokinetic parameters Each point represents the average of six results.
124 CH. 10] CONTROLLED DELIVERY OF THEOPHYLLINE Fig. 5—In vitro release profile of micromatrices (particle size , 770 µm; core:polymer ratio, 1:2): ●, RS 100; ○, RSPM; ▲, S 100; □, L 100.
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PHARMACEUTICAL TECHNOLOGY Controlle
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3 TABLET MACHINE INSTRUMENTATION IN
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First published in 1991 by ELLIS HO
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7 10 Controlled delivery of theophy
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Slow and steady wins the race Poems
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1 Influence of drug solubility in t
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CH. 1] INFLUENCE OF DRUG SOLUBILITY
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24 MATRIX FORMULATIONS [CH. 2 MATER
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26 MATRIX FORMULATIONS [CH. 2 Fig.
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28 MATRIX FORMULATIONS [CH. 2 Table
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30 MATRIX FORMULATIONS [CH. 2 The e
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34 CH. 3] THE FORMULATION OF SUSTAI
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4 Statistical optimization of a con
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MATRIX FORMULATIONS [CH. 4 45 (4) G
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MATRIX FORMULATIONS [CH. 4 47 Fig.
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Columns 1-4 lead to the matrix of e
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MATRIX FORMULATIONS [CH. 4 51 Table
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MATRIX FORMULATIONS [CH. 4 53 Fig.
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Fig. 5—Linearization of the relea
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58 MATRIX FORMULATIONS [CH. 5 Pevik
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60 MATRIX FORMULATIONS [CH. 5 The d
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6 Controlled release matrix tablets
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Page 133 and 134: 132 CH. 12] BIODEGRADABLE POLYMERS
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174 IMPLANTS [CH. 16 times with 5 m
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176 IMPLANTS [CH. 16 noted that the
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178 IMPLANTS [CH. 16 Fig. 1—The e
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180 IMPLANTS [CH. 16 Table 3—Tobr
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184 CH. 17] SILICON MATRIX SYSTEMS
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192
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194 INDEX dry granulation, 43 elect
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Pharmaceutical Technology: Controlled Drug Release, Volume 2

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