Pharmaceutical Technology: Controlled Drug Release, Volume 2

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MULTIPARTICULATES [CH. 13 149 Fig. 5—‘Higuchi’ plot of the release of phenobarbitone from phenobarbitone-DL-PLA tablets. Systems and ratios: microcapsules 1:1; 2:1; matrices 1:1; 2:1; compressive forces (a) 2 kN, (b) 5 kN and (c) 10 kN. Dissolution conditions: Buffer pH2; stirring rate, 100 rev min −1 ; t=37°C. REFERENCES 1 [] V.H.Lee and J.R.Robinson, in J.R.Robinson (ed.), Sustained and Controlled Release Drug Delivery Systems, Dekker, New York, 1978, p. 123. 2 [] W.A.Ritschel, in E.J.Ariens (ed.), Drug Design, Vol. IV, Academic Press, New York, 1973, p. 37. 3 [] D.A.Wood, in A.T.Florence (ed.), Materials Used in Pharmaceutical Formulation, Blackwell, London, 1984, p. 77. 4 [] R.K.Kulkarni, K.C.Pani, C.Neuman and F.Leonard, Arch. Surg., 93, 839 (1966). 5 [] S.Yolles, D.J. E.Eldridge and J.H. R.Woodland, Polym. News, 1, 9 (1971). 6 [] L.R.Beck, D.R.Cowsar, D.H.Lewis, J.W.Gibson and C.E.Flowers, Am. J. Obstet. Gynecol, 135, 419 (1979).
150 CH. 13] A COMPARISON OF DISSOLUTION PROPERTIES Fig. 6—‘Higuchi’ plot of the release of phenobarbitone from phenobarbitone-DL-PLA tablets. Systems and ratios: microcapsules 1:1; 2:1; matrices 1:1; 2:1; compressive forces (a) 2 kN, (b) 5 kN and (c) 10 kN. Dissolution conditions: Buffer pH 7; stirring rate, 100 rev min −1 ; t=37°C. 7 [] L.R.Beck, D.R.Cowsar, D.H.Lewis, R.J.Cosgrove, C.T.Riddel, S.L. Lowry and T. Epperly Fertil. Steril, 31(5), 545 (1979). 8 [] S.Yolles, T.D.Leafe, J.H.R. Woodland and F.J.Meyer, J. Pharm. Sci, 64(2), 348 (1975). 9 [] D.L.Wise, J.D.Greser and G.J.McCormick, J. Pharm. Pharmacol., 31, 201 (1979). 10 [] N.Wakiyama, K.Juni and M.Nakano, Chem. Pharm. Bull., 29(11), 3363 (1981). 11 [] K.Suzuki and J.C.Price, J. Pharm. Sci, 74(1), 21 (1985). 12 [] H.J.Krause, A.Schwarz and P.Rohdewald, Int. J. Pharm., 27, 145 (1985). 13 [] S.Benita, J.P.Benoit, F.Puisieux and C.Thies, J. Pharm. Sci, 73(12), 1721 (1984). 14 [] R.K.Kulkarni, E.G.Moore, A.F.Hegyeli and F.J.Leonard, Biomed. Mater. Res., 5, 169 (1971).
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PHARMACEUTICAL TECHNOLOGY Controlle
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3 TABLET MACHINE INSTRUMENTATION IN
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First published in 1991 by ELLIS HO
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7 10 Controlled delivery of theophy
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Slow and steady wins the race Poems
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1 Influence of drug solubility in t
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CH. 1] INFLUENCE OF DRUG SOLUBILITY
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24 MATRIX FORMULATIONS [CH. 2 MATER
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26 MATRIX FORMULATIONS [CH. 2 Fig.
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28 MATRIX FORMULATIONS [CH. 2 Table
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30 MATRIX FORMULATIONS [CH. 2 The e
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34 CH. 3] THE FORMULATION OF SUSTAI
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4 Statistical optimization of a con
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MATRIX FORMULATIONS [CH. 4 45 (4) G
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MATRIX FORMULATIONS [CH. 4 47 Fig.
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Columns 1-4 lead to the matrix of e
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MATRIX FORMULATIONS [CH. 4 51 Table
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MATRIX FORMULATIONS [CH. 4 53 Fig.
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Fig. 5—Linearization of the relea
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58 MATRIX FORMULATIONS [CH. 5 Pevik
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60 MATRIX FORMULATIONS [CH. 5 The d
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6 Controlled release matrix tablets
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CH. 6] CONTROLLED RELEASE MATRIX TA
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7 A new ibuprofen pulsed release or
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CH. 7] A NEW IBUPROFEN PULSED RELEA
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90 CH. 8] TOPICAL RELEASE AND PERME
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Page 99 and 100: 98 CH. 8] TOPICAL RELEASE AND PERME
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Page 185 and 186: 184 CH. 17] SILICON MATRIX SYSTEMS
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Page 195 and 196: 194 INDEX dry granulation, 43 elect
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Pharmaceutical Technology: Controlled Drug Release, Volume 2

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