Trimellitate Category; Revised Summaries - US Environmental ...

ACUTE IN-L4lA’~lON TOXJCJTY
+ Identity: Tris(Z-eUlylhexyl}ben~ne-1,2,4-tricarboxylatc
. Rems rks: Source: Nouplaz 6959, Batch No. 39049 .
Purity: 98.95%
. Rfethod: Not specified
. c&P: YfZ.5
. Year: 1982
+ Species: Rat
+ Stmin: crj: CD(SD)
l Doseshmccnlrahn Icveis; 2,600 m&‘m3
c sex: MaIe & Female
* Post tsxposut~ observlation period:Two weeks.
. Slatistid meLhods: Not appIicable because,of no fstalirq’.
RJWMRKS FIELD FOR TEST CONDI’MOIW
Study Design: I&al&on Ckanrbm: A 0.5mS stainless sleel inhalation chamber was used.
( Youg and Bertke, Cincirwiti, Ohio)
The I~SI compound atmosphere was geneTared directly into Ihe chamber by
means of Jet NeW izer Mechanism. ChamberconrsenWalions were
monitcvc~ by a fiheer paperlgrauimetric techniqueapproximately every 30
min during the exposure period.
The HEPA filtered chamber air-flow was maintained between 10 ID 20 air
changes per hour during lhe exposure period wilh the chamber under
slightly negative presswe.
The temperature in rhe chamber was maintained at 69-75 degree F with
relative humidity of D-50%
Satellite group mad reasm~ they were added: None
Clinical absemuhwspa$mnad und fmpcncy;
Afw the exposure, all animals were observed daily for 14 days for clinical
signs of toxicity. Body wzights were recorded prior 10 exposure and weekly
thereafler. All animals were subjecled IO necrapsy at bxminalion of the
study.