Trimellitate Category; Revised Summaries - US Environmental ...

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IUCLID Data Set Existing Chemical : ID: 53894-23-8 CAS No. : 53894-23-8 EINECS Name : triisononyl benzene-l ,2,4-tricarboxylate EINECS No. : 258-847-9 TSCA Name : 1,2,4-Benzenetricarboxylic acid, triisononyl ester Molecular Formula : C36H6006 Producer Related Part Company Creation date Substance Related Part Company Creation date Memo Printing date Revision date Date of last Update Number of Pages : 11 Chapter (profile) Reliability (profile) : Flags (profile) : ExxonMobil Biomedical Sciences Inc. : 02.11.2000 : ExxonMobil Biomedical Sciences Inc. : 02.11.2000 : ACC Phthalate Esters Panel HPV Testing Group : 15.03.2002 : 30.10.2001 1 /II
! 1. General Information Id 53894-23-8 1 .O.l OECD AND COMPANY INFORMATION Type Name Partner Date Street Town Country Phone Telefax Telex Cedex Remark Flag 26.10.2001 lead organisation ACC Phthalate Esters Panel HPV Testing Group Dr. Marian Stanley 1300 Wilson Blvd. 22209 Arlington, VA United States (703) 741-5623 (703) 741-6091 1.1 GENERAL SUBSTANCE INFORMATION Substance type Physical status Purity 09.10.2001 1 .I .O DETAILS ON TEMPLATE Comment Remark Date 1503.2002 The American Chemistry Council Phthalate Esters Panel sponsoring this test plan includes the following member companies: Eastman Chemical Company ExxonMobil Chemical Company Sunoco Chemicals Teknor Apex Company Critical study for SIDS endpoint : organic : liquid % wlw This chemical is part of the Trimellitate category. The category includes the following four CAS numbers: 3319-31-1, 27251-75-8, 53894-23-8 and 67989-23-5. DESCRIPTION OF THE TRIMELLITATES CATEGORY The trimellitates comprise a family of chemicals synthesized by esterifying trimellitic anhydride with alcohols with average carbon numbers ranging from approximately C7-CIO, in the presence of an acid catalyst. The category includes the four trimellitates: 3319-31-l (TOTM), 27251-75-8 (TIOTM), 53894-23-8 (TINTM), and 67989-23-5 (DOTM). Trimellitates in this category are all 1,2,4-benzenetricarboxylic acids with side chain ester groups ranging from C8 to CIO. The structural formula for trimellitates varies somewhat depending on the isomeric composition of the alcohols used in their manufacture. The specific alcohols used are 2-ethylhexanol (TOTM), iso-octyl alcohol (TIOTM), iso-nonyl alcohol (TINTM), and a mixture of linear and branched decyl (40%) and octyl (60%) alcohols (DOTM). Trimellitates are colorless to slightly yellow liquids with high boiling points (> 25OoC) and low vapor pressures; properties which contribute to their high physical stability. They are readily soluble in most organic solvents and miscible with alcohol, ether and most oils, but essentially insoluble in 2111 . . - -.--- -
Page 1 and 2: IUCLID Data Set Existing Chemical :
Page 3 and 4: 1. General Information Id 3319-31-1
Page 5 and 6: 2. Physico-Chemical Data Id 3319-31
Page 7 and 8: 3. Environmental Fate and Pathways
Page 11 and 12: 5. Toxicity Id 3319-31-1 5.1 .I ACU
Page 13 and 14: 5. Toxicity Id 3319-31-1 Test condi
Page 15 and 16: 6. References Id 3319-31-1 (3) (4)
Page 19 and 20: 1. General Information Id 27251-75-
Page 23 and 24: c 3. Environmental Fate and Pathway
Page 25 and 26: 5. Toxicity Id 27251-75-8 51.1 ACUT
Page 27: 7. Risk Assessment Id 27251-75-8 7.
Page 31 and 32: i 2. Physico-Chemical Data Id 53894
Page 35 and 36: - 4. Ecotoxicity 4.1 ACUTE/PROLONGE
Page 37 and 38: 6. References Id 53894-23-8 Date 15
Page 41 and 42: 1. General Information Id 67989-23-
Page 47 and 48: 5. Toxicity Id 67989-23-5 5.1 .I AC
Page 49 and 50: 7. Risk Assessment Id 67989-23-5 7.
Page 51 and 52: Summary of SIDS Information on Trim
Page 53 and 54: 3319311S~AP910.doc I ll I The Macka
Page 55 and 56: 4.5.2 4.6.1 4.6.2 4,6.3 Ft!zT 5.1.1
Page 57 and 58: 1. IDENTITY IUPAC Name: CM Number:
Page 59 and 60: EKE dw Esrimated Human EXP~H.IJ~ Lo
Page 61 and 62: Chromosomal aberralion lest by OECD
Page 63 and 64: I Fidl __-__________. - . .._. -..-
Page 65 and 66: Eastman Kodak. Absorption sncl melA
Page 67 and 68: TJZST SUBSTANCE . lden Lily: h R~ma
Page 69 and 70: l Idenlily: . Rcma rks: METHOD . Me
Page 71: DRAFT ENV,‘JM/EXCH(99)13 VAPOR PR
Page 74 and 75: I Rcmnrks: -. _ - - -
Page 76: --. TEST SUTSTANCE + Tdcn tily; . I
Page 80 and 81:
4 Kelia bilities: Key sludy l Remar
Page 83 and 84:
w + l + + l + + l + Method: VP@: GL
Page 85:
--. - ,-.-.. .----_ -. -_ l Remarks
Page 88 and 89:
CONCLUSIONS DATA QUALITY Mortality
Page 90 and 91:
DRAFT EI’WJM/EXCHI[99)13 TIEST WE
Page 92 and 93:
DATA QUMJTY . Rtliabilitie~: Khiscb
Page 94 and 95:
DRAFT ENV/JM/EXCH(99)23 REsuLTs Nom
Page 96 and 97:
TEST SUBSTANCE 1 Identity: Remarks:
Page 98 and 99:
DRAFT’ ENV/JMIEXCH(99)13 c DATA Q
Page 100 and 101:
DRAFf ENV/3M/EXCH(99)13 Nominal cxu
Page 103 and 104:
ACUTE ORAL. TOXICITY DRAFT ENV/JM/E
Page 105 and 106:
ACUTE IN-L4lA’~lON TOXJCJTY + Ide
Page 107 and 108:
mST SUBSTANCE . Idcnlity: ~js(2-eth
Page 109 and 110:
Diet - Wqne 15% Rabbit Rzltion and
Page 111 and 112:
TEST SUBSTANCE l lden Lily: Tris(2-
Page 113 and 114:
t - . KEFERENCES GENERAL REmRKS ~uu
Page 115 and 116:
SENSIT~ ZATI ON TJ3T SUBSTANCE . Id
Page 117 and 118:
I Iden tilyr . Rems rks: METHOD . l
Page 119 and 120:
increased in the TOTM and DEEP trea
Page 121 and 122:
IZST SUBSTANCE I Edcntity: l Remark
Page 123 and 124:
Organ weighr chunges: ac A? md qfdm
Page 125 and 126:
.l_.“. _.,“^---“~~, RESULTS P
Page 127 and 128:
JDJ-LGFI’ EJWJM/EXC.X(99)13 No. o
Page 129 and 130:
DRAFT ENV/JM/EXCH(99)13 Female Day
Page 131 and 132:
1 Genotoxic clbttsr With metabolic
Page 133 and 134:
IIRAn ENV/JMfiXW(99)13 GENETIC TOXI
Page 135 and 136:
air side air-water hfl’C 5 soil a
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