Ermolaeva’s results <strong>and</strong> concluded that, <strong>in</strong>stead <strong>of</strong> refut<strong>in</strong>g <strong>the</strong>Mendelian law, she completely confirmed it. There also, withoutm<strong>in</strong>utely analys<strong>in</strong>g En<strong>in</strong>’s paper, Kolmogorov implied that his resultsare doubtful because <strong>the</strong>y confirmed that law too f<strong>in</strong>ely.In a popular scientific booklet, I [iii] thought it expedient to rem<strong>in</strong>dreaders about Kolmogorov’s paper <strong>and</strong> supplemented it by treat<strong>in</strong>gEn<strong>in</strong>’s results. Alimov treated <strong>the</strong> same data o<strong>the</strong>rwise <strong>and</strong> formulateda number <strong>of</strong> objections. He directed <strong>the</strong>m to me alone although a part<strong>of</strong> <strong>the</strong>m to <strong>the</strong> same extent concerned Kolmogorov’s calculations. Ibeg<strong>in</strong> with <strong>the</strong> objection which I underst<strong>and</strong> <strong>and</strong> consider essential.He notes that <strong>in</strong> many cases <strong>the</strong> families considered by Ermolaevawere small (not more than 10 observations). Then <strong>the</strong> normalapproximation <strong>of</strong> <strong>the</strong> frequencies <strong>of</strong> a certa<strong>in</strong> phenotype <strong>in</strong>troduced byKolmogorov ought to be very rough. In particular, <strong>the</strong> presence <strong>of</strong>normed frequencies smaller than − 3 which I [iii] considered assignificant deviations from <strong>the</strong> Mendelian law can be expla<strong>in</strong>ed. asAlimov believes, by <strong>the</strong> asymmetry <strong>of</strong> <strong>the</strong> b<strong>in</strong>omial law. Alimovdeclared that my conclusion was wrong (that was somewhat hastily, heshould have said unjustified). Any student <strong>of</strong> a technical <strong>in</strong>stitute, as hestates, would have avoided such a mistake caused by <strong>the</strong> generalcorruption <strong>of</strong> concepts due to <strong>the</strong> application <strong>of</strong> <strong>the</strong> non-Miseslanguage <strong>and</strong> <strong>the</strong> rituals <strong>of</strong> ma<strong>the</strong>matical statistics.Actually, everyth<strong>in</strong>g is much simpler. Before prepar<strong>in</strong>g my booklet,I did not acqua<strong>in</strong>t myself with Ermolaeva’s paper which was notreadily available. Now, however, s<strong>in</strong>ce her data became an object <strong>of</strong>discussion, I had a look at that source. The data on <strong>the</strong> assortment <strong>in</strong>separate families are provided <strong>the</strong>re <strong>in</strong> Tables 4 <strong>and</strong> 6. In Table 4 <strong>the</strong>families are numbered from 1 to 100, but for some unknown reasonnumbers 50 <strong>and</strong> 87 are omitted. In Table 6, <strong>the</strong> number<strong>in</strong>g beg<strong>in</strong>s with22 <strong>and</strong> cont<strong>in</strong>ues until 148, but numbers 92, 95, 115, 127, 144 areabsent. At <strong>the</strong> same time, <strong>the</strong> table show<strong>in</strong>g <strong>the</strong> total, states 100 <strong>and</strong>127 families respectively.Kolmogorov <strong>in</strong>serted a venomous pert<strong>in</strong>ent remark; he counted 98families <strong>in</strong> <strong>the</strong> first, <strong>and</strong> 123 (actually, 122) <strong>in</strong> <strong>the</strong> second table. Thegeneral style <strong>of</strong> her contribution, let me say it frankly, is abom<strong>in</strong>able.The author obviously does not underst<strong>and</strong> <strong>the</strong> mean<strong>in</strong>g <strong>of</strong> <strong>the</strong> errorscalculated by biometric methods for <strong>the</strong> number <strong>of</strong> assortments. It isquite clear that her data do not really deserve to be seriouslyconsidered.However, if only discuss<strong>in</strong>g Ermolaeva’s tables such that <strong>the</strong>y are,Alimov is still unjustly reproach<strong>in</strong>g me for discover<strong>in</strong>g non-existentdeviations from <strong>the</strong> Mendelian law. Indeed, Table 4 <strong>in</strong>cludes a result<strong>of</strong> assortment 0:17, <strong>and</strong> 0:10 <strong>in</strong> Table 6 <strong>in</strong>stead <strong>of</strong> <strong>the</strong> expected ratio3:1. Their probabilities are 4 −17 <strong>and</strong> 4 −10 respectively so that, hav<strong>in</strong>g200 plus trials, such events could not have occurred.Concern<strong>in</strong>g both Kolmogorov’s <strong>and</strong> my own treatment, I wouldlike to <strong>in</strong>dicate that, <strong>in</strong> spite <strong>of</strong> Alimov’ op<strong>in</strong>ion, correct scientificresults are possibly <strong>of</strong>ten obta<strong>in</strong>ed not because we do everyth<strong>in</strong>gproperly, but ow<strong>in</strong>g to some special luck.I did not underst<strong>and</strong> <strong>the</strong> mean<strong>in</strong>g <strong>of</strong> Alimov’s objection to <strong>the</strong>calculation <strong>of</strong> <strong>the</strong> confidence level. From <strong>the</strong> times <strong>of</strong> Laplace, after136
obta<strong>in</strong><strong>in</strong>g a deviation from <strong>the</strong> <strong>the</strong>ory assumed to be valid, scientistshave been attempt<strong>in</strong>g to calculate, if possible, <strong>the</strong> probability <strong>of</strong> adeviation not less than that. If that probability was high, 1/2, say,everyth<strong>in</strong>g was <strong>in</strong> order; o<strong>the</strong>rwise, suppos<strong>in</strong>g that its order was1/1000, it was advisable to look for <strong>the</strong> cause <strong>of</strong> <strong>the</strong> deviation. If,f<strong>in</strong>ally, it was moderate, its order be<strong>in</strong>g 1/10, say, <strong>the</strong> case wasdoubtful <strong>and</strong> a f<strong>in</strong>al decision impossible. Can we object to such k<strong>in</strong>d <strong>of</strong>apply<strong>in</strong>g <strong>the</strong> confidence level?I do not underst<strong>and</strong> Alimov’s concept <strong>of</strong> <strong>in</strong>dependence ei<strong>the</strong>r. On p.80 he th<strong>in</strong>ks that secondary trials, that is, data on <strong>the</strong> assortment <strong>of</strong><strong>in</strong>dications <strong>in</strong> different families, unconnected with each o<strong>the</strong>r, can bestatistically dependent. But how could that occur with <strong>the</strong> outcomes <strong>of</strong>different trials unconnected with each o<strong>the</strong>r? If as a result <strong>of</strong> one trialevents A <strong>and</strong> B can ei<strong>the</strong>r happen or fail, <strong>the</strong>y can be statisticallydependent <strong>and</strong>, when treat<strong>in</strong>g this dependence accord<strong>in</strong>g to Mises, weshould use a s<strong>in</strong>gle record. But <strong>in</strong> case <strong>of</strong> two absolutely different trialswe should apparently <strong>in</strong>troduce someth<strong>in</strong>g like a direct product <strong>of</strong> tworecords.F<strong>in</strong>ally, concern<strong>in</strong>g my treatment <strong>of</strong> En<strong>in</strong>’s data, Alimov remarksfirst <strong>of</strong> all that his number <strong>of</strong> families is so small (11 + 14 = 25), that<strong>the</strong>ir treatment did not warrant <strong>the</strong> waste <strong>of</strong> ei<strong>the</strong>r time or paper with aspecial non-l<strong>in</strong>ear scale. I will answer that by stat<strong>in</strong>g that, on <strong>the</strong>contrary, I aimed at show<strong>in</strong>g that <strong>the</strong> image <strong>of</strong> a distribution functionunlike that <strong>of</strong> a histogram allows to obta<strong>in</strong> sensible results even whenhav<strong>in</strong>g such a small sample size.Then, Alimov states that it was possible to arrive at my conclusionsby compil<strong>in</strong>g an extended sample 1 . To some extent this is correct, butto some extent wrong. After tak<strong>in</strong>g samples <strong>of</strong> about <strong>the</strong> same size, <strong>the</strong>frequencies <strong>in</strong> En<strong>in</strong>’s second sample will be closer to <strong>the</strong> <strong>the</strong>oreticalmagnitudes than Ermolaeva’s similar frequencies. This is seen <strong>in</strong>Alimov’s table (1978, p. 78). It can be <strong>the</strong>refore concluded, ifErmolaeva’s data are considered as a st<strong>and</strong>ard, that <strong>the</strong>re is sometrouble with En<strong>in</strong>’s materials.However, after calculat<strong>in</strong>g <strong>the</strong> chi-squared statistic (Tutubal<strong>in</strong> [iii]),a st<strong>and</strong>ard is not needed. Actually, Alimov (1978, pp. 80 – 81)believes that En<strong>in</strong>’s data should be treated not by means <strong>of</strong> <strong>the</strong> normaldistribution <strong>of</strong> <strong>the</strong> normed frequencies, but by a more subtle model. Inpr<strong>in</strong>ciple, I completely agree, only that model should not be a mixture<strong>of</strong> b<strong>in</strong>omial distributions (Alimov, p. 80, formula (21)), but it shoulddirectly consider <strong>the</strong> actual numerical strength <strong>of</strong> <strong>the</strong> families. A series<strong>of</strong> b<strong>in</strong>omial trials would be obta<strong>in</strong>ed hav<strong>in</strong>g a known number <strong>of</strong> trials<strong>and</strong> a known probability <strong>of</strong> success. Underst<strong>and</strong>ably, such a model isbarely convenient <strong>and</strong> <strong>the</strong>refore <strong>the</strong> stupidest Monte Carlo method 2will apparently be most effective for calculat<strong>in</strong>g <strong>the</strong> various pert<strong>in</strong>entprobabilities. Thus, for example, <strong>the</strong> true distribution <strong>of</strong> <strong>the</strong>Kolmogorov statistic or some o<strong>the</strong>r statistic measur<strong>in</strong>g <strong>the</strong> deviationfrom <strong>the</strong> Mendelian law can be determ<strong>in</strong>ed. S<strong>in</strong>ce such statistics arera<strong>the</strong>r diverse, we conclude that not only <strong>the</strong> electron or <strong>the</strong> atom butalso <strong>the</strong> certa<strong>in</strong>ly carelessly constructed Ermolaeva’s tables are<strong>in</strong>exhaustible 3 .137
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Studies in the History of Statistic
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Introduction by CompilerI am presen
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(Lect. Notes Math., No. 1021, 1983,
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sufficiently securely that a carefu
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is energy?) from chapter 4 of Feynm
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demand to apply transfinite numbers
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for stating that Ω consists of ele
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chances to draw a more suitable apa
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Let the space of elementary events
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2.3. Independence. When desiring to
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Eξ = ∑ aipi.Our form of definiti
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absolutely precisely if the pertine
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where x is any real number. If dens
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probability can be coupled with an
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Nowadays we are sure that no indepe
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λ = λ(T)with λ(T) being actually
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(1/B n )(m − A n )instead of the
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along with ξ. For example, if ξ i
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µ( − p0) ÷np0 (1 − p0)nhas an
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distribution of the maximal term |s
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ξ (ω) + ... + ξ (ω)n1n{ω :|
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P{max ξ(t) ≥ x} = 0.01, 0 ≤ t
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1. This example and considerations
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IIV. N. TutubalinTreatment of Obser
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structure of statistical methods, d
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Suppose that we have adopted the pa
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and the variances are inversely pro
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It is interesting therefore to see
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is applied with P(t) being a polyno
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ut some mathematical tricks describ
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It is clear therefore that no speci
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of various groups of machines, and
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nnA(λ) x sin λ t, B(λ) = x cosλ
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of the mathematical model of the Br
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dF(λ) = f (λ) dλ, so that B( t
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usually very little of them. Indeed
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Reasoning based on common sense and
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answering that question is extremel
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