Aging Aging

More documents

Recommendations

Info

Immunogenetics and Life-Span 339Table 10HLA-B SSOP PatternsHLA-B 7 0 0 0 0 0 0 1 1 1 1 2 2 2 2 3 3 3 3 3 3 3 3 3 3 3 3 4 4 4allele . 7 7 8 8 8 8 3 3 4 8 7 7 7 7 5 5 5 5 5 5 7 7 8 8 9 9 0 0 02 0 0 0 0 0 0 0 0 0 0 . 0 . 0 . 1 1 2 0 0 0 0 . . 0 . 03 8 1 2 3 4 1 3 1 2 2 8 3 8 4 5 9 0 1 2 1 2 2 3 1 2 5/ /0 1Probe 2 801 + + + +02 + + + + + + + +05 + + + + + + + + +07 + +09 + + + + + + + + + + + + + + + +10 +12 + + + +1820 + + + + +21 + + + + + + + + + + + + + + + + + + +22 + + +23 + + +24 + + + + + + + +26 + + + + +2728 +30 + +31 + + + +32 +33343536 +3738394041 +42 +43 + + + + + + + + + + + + + + + + +44 + + + +45 + + + + + + +46 + + + + + + + + + + +4748 + + + +49 + + + +(continued)
340 Middleton, Curran, and WilliamsTable 10 (cont.)HLA-B 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 5 5 5 5 5 5 5 5 5 5 5allele 0 0 1 1 2 4 4 4 4 4 4 4 5 6 7 7 8 8 9 0 1 1 1 2 3 4 5 5 5 50 0 0 0 0 0 . 0 0 0 0 1 0 0 0 0 0 0 0 0 . 0 0 0 . 0 0 07 8 1 2 1 2 1 4 5 6 8 0 1 1 1 2 1 2 1 1 1 5 7 1 1 3 4 6/ /0 0Probe 3 801 + + + + + + + + + + + + + +02 + + + + + +05 + + + + + +07 + +09 + + + + + + +10 + + + + +1218 + +20 + + + + + +21 + + + + + + + + + + + + + + + +22 +23 + + + + + + +24 + + + + + + + + + + + + + + + +26 + + + + + +27 + + + +2830 + + + +313233 +3435363738 + + +39 + + + + +40 + + + +4142 + +43 + + + + + + + + + + + + + + + + + + +4445 + + + + + + + + + + + + + + + +46 + + + + + + + + +47 + + + + + + + +48 + + +49 + +(continued)
Page 7:
6 Strehlerlead to possible death si
Page 10 and 11:
Understanding Aging 9the intestine
Page 12 and 13:
Understanding Aging 117. Do long-li
Page 14 and 15:
Understanding Aging 13is, the great
Page 16 and 17:
Understanding Aging 15While this re
Page 18 and 19:
Understanding Aging 172. Pearl, R.
Page 20 and 21:
Understanding Aging 1945. Perovic,
Page 22 and 23:
24 Cristofalo, Volker, and Allenmen
Page 24 and 25:
26 Cristofalo, Volker, and Allenrec
Page 26 and 27:
28 Cristofalo, Volker, and Allenski
Page 28 and 29:
30 Cristofalo, Volker, and AllenTab
Page 30 and 31:
Page 32 and 33:
34 Cristofalo, Volker, and AllenNa
Page 34 and 35:
Page 36 and 37:
38 Cristofalo, Volker, and Allentak
Page 38 and 39:
40 Cristofalo, Volker, and Allenb.
Page 40 and 41:
42 Cristofalo, Volker, and Allenand
Page 42 and 43:
44 Cristofalo, Volker, and AllenRef
Page 44 and 45:
46 Cristofalo, Volker, and Allen33.
Page 46 and 47:
48 Cristofalo, Volker, and Allen61.
Page 48 and 49:
50 Cristofalo, Volker, and Allenhum
Page 50 and 51:
52 Cristofalo, Volker, and Allen125
Page 52 and 53:
54 Pawelecdiluted cells on an irrad
Page 54 and 55:
56 Pawelec3. Method3.1. Source of C
Page 56 and 57:
58 Pawelecweekly or fortnightly sub
Page 58 and 59:
60 Pawelection, the VERUM Foundatio
Page 60 and 61:
Telomeres and Replicative Senescenc
Page 62 and 63:
Page 64 and 65:
Page 66 and 67:
Page 68 and 69:
Detection of Molecular Events 715De
Page 70 and 71:
Detection of Molecular Events 73hav
Page 72 and 73:
Detection of Molecular Events 75Fig
Page 74 and 75:
Detection of Molecular Events 772.
Page 76 and 77:
Detection of Molecular Events 79Fig
Page 78 and 79:
Page 80 and 81:
Page 82 and 83:
86 Kirk and Millerexperiments on un
Page 84 and 85:
88 Kirk and MillerFig. 1. (A) Analy
Page 86 and 87:
90 Kirk and MillerFurthermore, limi
Page 88 and 89:
92 Kirk and Millersufficiently dilu
Page 90 and 91:
94 Kirk and Miller4. Run samples on
Page 92 and 93:
96 Kirk and Miller16. Lange-Carter,
Page 94 and 95:
98 Engel, Adibzadeh, and PawelecPCR
Page 96 and 97:
100 Engel, Adibzadeh, and Pawelec5.
Page 98 and 99:
102 Engel, Adibzadeh, and PawelecTa
Page 100 and 101:
104 Engel, Adibzadeh, and PawelecTa
Page 102 and 103:
106 Engel, Adibzadeh, and Pawelecam
Page 104 and 105:
Page 106 and 107:
110 Engel, Adibzadeh, and Pawelecfo
Page 108 and 109:
Page 110 and 111:
114 Engel, Adibzadeh, and Pawelecha
Page 112 and 113:
Xenobiotic-Metabolizing Enzymes 119
Page 114 and 115:
Page 116 and 117:
Page 118 and 119:
Page 120 and 121:
Page 122 and 123:
Page 124 and 125:
Assessing Antioxidant Status 1339As
Page 126 and 127:
Assessing Antioxidant Status 135Fig
Page 128 and 129:
Assessing Antioxidant Status 137Tab
Page 130 and 131:
Assessing Antioxidant Status 139add
Page 132 and 133:
Assessing Antioxidant Status 14121.
Page 134 and 135:
Comet Assay of DNA Damage 14310Meas
Page 136 and 137:
Comet Assay of DNA Damage 145contro
Page 138 and 139:
Comet Assay of DNA Damage 1476. Lys
Page 140 and 141:
Comet Assay of DNA Damage 1494. Gen
Page 142 and 143:
Comet Assay of DNA Damage 151anode
Page 144 and 145:
Comet Assay of DNA Damage 1535. As
Page 146 and 147:
Comet Assay of DNA Damage 15515. In
Page 148 and 149:
Comet Assay of DNA Damage 15720. Co
Page 150 and 151:
160 van der Schanswithin 1 h, after
Page 152 and 153:
162 van der Schans10. High-binding
Page 154 and 155:
164 van der Schans3. Neutralize aft
Page 156 and 157:
166 van der SchansThe calculations
Page 158 and 159:
8-oxoguanine Levels in Nuclear DNA
Page 160 and 161:
Page 162 and 163:
Page 164 and 165:
Page 166 and 167:
Mutation and the Aging Process 1791
Page 168 and 169:
Mutation and the Aging Process 181m
Page 170 and 171:
Mutation and the Aging Process 183b
Page 172 and 173:
Page 174 and 175:
Page 176 and 177:
190 HouThe HPRT mutational spectrum
Page 178 and 179:
192 Houamplifications are carried o
Page 180 and 181:
194 Hou4. Reading: Load 10 µL of t
Page 182 and 183:
196 Hou4.2. MP-PCRUse preferably DN
Page 184 and 185:
Susceptibility of LDL to Oxidation
Page 186 and 187:
Page 188 and 189:
Page 190 and 191:
Page 192 and 193:
Page 194 and 195:
Analysis of Pentosidine 20916Measur
Page 196 and 197:
Analysis of Pentosidine 211Fig. 2.
Page 198 and 199:
Analysis of Pentosidine 213Fig. 4.
Page 200 and 201:
Analysis of Pentosidine 2152. Preci
Page 202 and 203:
Analysis of Pentosidine 2177. Nagar
Page 204 and 205:
222 Miquellipoperoxides and malonal
Page 206 and 207:
224 Miquelat 4°C. Protect this sol
Page 208 and 209:
226 Miquel3.1. Animal AnesthesiaMed
Page 210 and 211:
228 Miquelsteps to carry out a conv
Page 212 and 213:
230 Miquelsuspending it over the so
Page 214 and 215:
232 Miquelcontrast, washing with bu
Page 216 and 217:
234 MiquelFig. 3. Electron microsco
Page 218 and 219:
Damage to Mitochondria 23718Causes
Page 220 and 221:
Damage to Mitochondria 239Fig. 1. E
Page 222 and 223:
Damage to Mitochondria 2412. To obt
Page 224 and 225:
Damage to Mitochondria 243synthesis
Page 226 and 227:
Mitochondrial DNA Mutations 24519An
Page 228 and 229:
Mitochondrial DNA Mutations 247F.P.
Page 230 and 231:
Mitochondrial DNA Mutations 249desi
Page 232 and 233:
Mitochondrial DNA Mutations 2514. M
Page 234 and 235:
Mitochondrial DNA Mutations 253Fig.
Page 236 and 237:
Mitochondrial DNA Mutations 25568°
Page 238 and 239:
Mitochondrial DNA Mutations 257Fig.
Page 240 and 241:
Mitochondrial DNA Mutations 2593. P
Page 242 and 243:
Mitochondrial DNA Mutations 261X-10
Page 244 and 245:
Mitochondrial DNA Mutations 26315.
Page 246 and 247:
Mitochondrial DNA Mutations 26520An
Page 248 and 249:
Mitochondrial DNA Mutations 267Tabl
Page 250 and 251:
Mitochondrial DNA Mutations 269muta
Page 252 and 253:
Mitochondrial DNA Mutations 2717. P
Page 254 and 255:
Mitochondrial DNA Mutations 2733.2.
Page 256 and 257:
Mitochondrial DNA Mutations 275that
Page 258 and 259:
Mitochondrial DNA Mutations 27711.
Page 260 and 261:
282 BeckmanWhatever the mechanism e
Page 262 and 263:
284 BeckmanT-cell adherence to vasc
Page 264 and 265:
286 BeckmanT3 hybridoma cells satis
Page 266 and 267: 288 BeckmanHaving identified a cand
Page 268 and 269: 290 Beckmanthe plates vigorously wi
Page 270 and 271: 292 Grubeck-Loebenstein, Saurwein-T
Page 288 and 289: NK Cell Function in Aging 31123Age-
Page 290 and 291: NK Cell Function in Aging 3135. Pet
Page 292 and 293: NK Cell Function in Aging 31518. Io
Page 294 and 295: NK Cell Function in Aging 3173.3. C
Page 296 and 297: NK Cell Function in Aging 3199mL of
Page 298 and 299: Immunogenetics and Life-Span 32124I
Page 300 and 301: Immunogenetics and Life-Span 323Tab
Page 302 and 303: Immunogenetics and Life-Span 325rea
Page 304 and 305: Immunogenetics and Life-Span 3273.
Page 308 and 309: Immunogenetics and Life-Span 3313.5
Page 326 and 327: Immunogenetics and Life-Span 349to
Page 328 and 329: 354 Yuto-implement intervention and
Page 330 and 331: 356 Yuof their quality control proc
Page 332 and 333: 358 Yugenesis of major diseases (1-
Page 334 and 335: Genetically Engineered Mice 36126Th
Page 336 and 337: Genetically Engineered Mice 363as t
Page 338 and 339: Genetically Engineered Mice 365in b
Page 340 and 341: Genetically Engineered Mice 367numb
Page 342 and 343: Genetically Engineered Mice 369mula
Page 344 and 345: Genetically Engineered Mice 371Othe
Page 346 and 347: Genetically Engineered Mice 373locu
Page 348 and 349: Genetically Engineered Mice 37537.
Page 350: Genetically Engineered Mice 377→
show all

Aging Aging

Create successful ePaper yourself

Delete template?

Save as template?