Anorectal Manometry in 3D NEW! - Swiss-knife.org
Anorectal Manometry in 3D NEW! - Swiss-knife.org
Anorectal Manometry in 3D NEW! - Swiss-knife.org
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formed 5 months later, aga<strong>in</strong> with a completely uneventful follow-up.<br />
Results: Colonic <strong>in</strong>farction <strong>in</strong> acute pancreatitis was first reported <strong>in</strong> 1945 by Moore et Castleman. The<br />
<strong>in</strong>cidence of colon <strong>in</strong>volvement <strong>in</strong> patients with acute pancreatitis is 3.3-15% and has a mortality rate<br />
of up to 54%. Direct spread of pancreatic enzymes and necrosis are the major cause for colonic pathology<br />
<strong>in</strong> acute pancreatitis. Cl<strong>in</strong>ical presentation may be difficult due to the symptoms of acute pancreatitis<br />
and especially abdom<strong>in</strong>al sepsis due to colonic perforation may be diagnosed too late. In order to<br />
reduce mortality early diagnosis and emergency surgery are mandatory. The treatment of choice is the<br />
resection of the affected segment with construction of a (temporary) split (ileo-) colostomy.<br />
Conclusion: Cl<strong>in</strong>icians should be aware of possible colonic <strong>in</strong>volvement and complications <strong>in</strong> acute<br />
pancreatitis.<br />
99.7<br />
Les filets composites double-face sont-ils si anod<strong>in</strong>s?<br />
A. Donad<strong>in</strong>i, S. Aellen, N. Demart<strong>in</strong>es, H. Vuilleumier (Lausanne)<br />
Objective: Les filets couverts respectivement par de la cellulose oxydée régénérée, du collagène porc<strong>in</strong><br />
ou des acides gras oméga-3 purifiés, peuvent être placés au contact direct des <strong>org</strong>anes <strong>in</strong>tra abdom<strong>in</strong>aux<br />
lors d’une réparation pariétale. Le revêtement anti adhérent n’est censé <strong>in</strong>duire, en théorie, aucune<br />
adhérence <strong>in</strong>tra péritonéale, tout en gardant sa fonction mécanique de renforcement pariétal. Le but<br />
de ce travail est de décrire les modifications <strong>in</strong> situ observée lors de ré-opérations au placement de filet<br />
composite <strong>in</strong>tra-péritonéaux.<br />
Methods: Au total 10 patients consécutifs ont été réopérés entre 2008 et 2009, 5 pour des récidives<br />
d’éventration, 1-2 ans après la mise en place de filets double-face <strong>in</strong>tra péritonéaux par laparoscopie<br />
et par laparotomie. C<strong>in</strong>q autres on nécessité une opération pour abdomen aigu.<br />
Results: Quatre récidives de hernie ont été traitées par mise en place de filets retro-musculaires selon la<br />
technique de Rives-Stoppa et une en position pré-péritonéale. Une cholécystectomie a été effectuée par<br />
laparoscopie. C<strong>in</strong>q adhésiolyses extensives ont été effectuées pour iléus mécanique et dans un cas,<br />
une résection grêle. D’importantes adhérences viscérales au niveau de l’implant ont été constatées<br />
chez les 10 patients (100%). Nous avons observé la non-<strong>in</strong>tégration du filet à la paroi, et également<br />
des <strong>in</strong>crustations du filet dans la séreuse et l’ensemble de la paroi du grêle.<br />
Conclusion: L’efficacité des filets composites double-face a été étudiée en majeure partie sur des<br />
modèles expérimentaux. Les résultats montrent une efficacité limitée de ces filets avec tendance augmentée<br />
aux récidives. La surface anti-adhérente démontre très peu d’adhérences <strong>in</strong>tra péritonéales<br />
à 7 jours, propriété totalement disparue à 30 jours. Suite à une phagocytose naturelle de la couche<br />
anti-adhérente, une formation d’adhérences est <strong>in</strong>duite qui pourrait être la cause de l’affaiblissement<br />
de la paroi abdom<strong>in</strong>ale par non-<strong>in</strong>corporation du matériel prothétique, favorisant a<strong>in</strong>si les récidives. Il<br />
n’existe actuellement aucune étude prospective randomisé chez l’homme, ni même rétrospective car<br />
peu de patient sont réopérés ou alors ce type de complications n’est pas rapporté. Les cas exposés<br />
ci-dessus confirment que l’utilisation de prothèses composites double-face n’empêche pas la formation<br />
d’adhérences <strong>in</strong>tra péritonéales et qu’ils ne doivent être utilisés que parcimonieusement dans des<br />
cas particulier.<br />
99.8<br />
Gastric band<strong>in</strong>g versus Roux-en-Y gastric bypass <strong>in</strong> non-superobese patients. A matched-case control<br />
study of 442 patients<br />
S. Romy 1 , V. Giusti 1 , J.-M. Calmes 1 , N. Demart<strong>in</strong>es 1 , M. Suter 2 ( 1 Lausanne, 2 Aigle- Monthey)<br />
Objective: Roux-en-Y gastric bypass (RYGBP) and gastric band<strong>in</strong>g (GB) are the two most popular<br />
bariatric procedures. Only few studies have compared their results and follow-up duration is usually<br />
limited to < 3 years. The aim of the present analysis is to assess and compare long-term outcome of<br />
both GB and RYGBP <strong>in</strong> term of complications and weight reduction. Our Hypotesis is that despite a<br />
lower immediate postoperative complication rate, GB <strong>in</strong> the long-term results <strong>in</strong> more complications<br />
than RYGB, and less weight loss.<br />
Methods: Prospective bariatric database s<strong>in</strong>ce 1995. Non-superobese GB patients were matched for<br />
sex, age and BMI to RYGBP patients. Follow-up considered up to five years.<br />
Results: 442 patients could be matched <strong>in</strong> 221 pairs. Mean age (38,6) and mean BMI (43) were identical<br />
between groups. Overall operative morbidity was significantly higher <strong>in</strong> the RYGBP group (17,2<br />
versus 5,4%, p < 0,001), but major morbidity was similar (3,6 versus 2,2%, p = 0,39). Significantly<br />
more patients developed long-term complications after GB (33% versus 20,3%, p = 0,002), and more<br />
required reoperations (24,4% versus 13,6%, p = 0,003). Reoperations were ma<strong>in</strong>ly due to <strong>in</strong>ternal hernias<br />
after RYGBP (87%), with no reversal, whereas 18,5% of the GB patients required band removal.<br />
Even <strong>in</strong>clud<strong>in</strong>g only patients who reta<strong>in</strong>ed their band, weight loss after RYGBP was significantly better<br />
throughout the study period, and the 5-year EBMIL was 77,6% and 63,6% (p = 0,001) after RYGBP<br />
and GB respectively.<br />
Conclusion: GB is associated with a smaller overall operative morbidity and similar major morbidity,<br />
but with more long-term complications, more reoperations, a significant number of reversal or conversion<br />
procedures, and reduced weight loss when compared with RYGBP. Five-year results of RYGBP are<br />
superior to GB and patients should be <strong>in</strong>formed accord<strong>in</strong>gly.<br />
99.9<br />
Liver transplantation for herpes simplex virus-<strong>in</strong>duced hepatitis: a SRTR registry-based study<br />
B. Moldovan, G. Mentha, P. Majno, T. Berney, I. Morard, E. Giostra, B. Wildhaber, Ph. Morel, C. Toso<br />
(Geneva)<br />
Objective: Herpes simplex virus (HSV)-<strong>in</strong>duced hepatitis is a rare, but severe disease, sometimes requir<strong>in</strong>g<br />
emergency liver transplantation. The aim of this registry-based study was to analyze the epidemiology<br />
and outcome of such transplantations.<br />
Methods: This study was based on the SRTR registry, a large nation-wide US registry (<strong>in</strong>clud<strong>in</strong>g all<br />
listed and/or transplanted patients <strong>in</strong> the US). All patients listed for liver transplantation for HSV hepatitis<br />
from October 1987 to May 2009 were <strong>in</strong>cluded. We first assessed all listed patients and then performed<br />
a case-control study, match<strong>in</strong>g each transplanted patients with 10 controls. Match<strong>in</strong>g criteria<br />
<strong>in</strong>cluded: age ±5 years, transplantation date ±6 months, MELD score ±5 po<strong>in</strong>ts, graft type: whole liver/<br />
split and transplant status: emergency/elective.<br />
Results: Dur<strong>in</strong>g the study period, 30 patients were listed for HSV hepatitis. Twelve were not transplanted,<br />
<strong>in</strong>clud<strong>in</strong>g seven spontaneous recovery and 5 deaths. The chance of recovery was significant higher<br />
<strong>in</strong> children (7/9) than <strong>in</strong> adults (0/3, p=0.017). Of the 18 transplanted patients, 10 were children and 8<br />
adults. Most transplants (15/18) were performed on an emergency basis, with a mean MELD score of<br />
28±13. The overall 5-year survival was 44%. In children, survival was similar between the HSV patients<br />
and the 180 matched controls (5-year survival: 69 vs. 64%, log-rank p=0.89). Conversely, survival was<br />
poor <strong>in</strong> adult HSV recipients, with 63% of them dy<strong>in</strong>g with<strong>in</strong> the first 12 months (5-year survival: 13 vs.<br />
59%, log-rank p=0.006). In addition, all three reported deaths <strong>in</strong> children were <strong>in</strong>dependent from HSV,<br />
while 4/7 adults deaths were <strong>in</strong>fection-related.<br />
Conclusion: Children listed for HSV hepatitis have a significantly better survival than adults both prior<br />
and after liver transplantation. While HSV fulm<strong>in</strong>ant hepatitis is an appropriate <strong>in</strong>dication for liver transplantation<br />
<strong>in</strong> children, it should only be performed <strong>in</strong> very selected adult patients.<br />
99.10<br />
Cont<strong>in</strong>uous peridural catheter analgesia improves <strong>in</strong>test<strong>in</strong>al motility but not early mobilisation after<br />
open colon surgery<br />
A. R<strong>in</strong>gger 1 , M. Worni 1 , A. Lechleiter 2 , M. Mastrocola 1 , U. Laffer 1 ( 1 Biel, 2 Berne)<br />
Objective: Cont<strong>in</strong>uous peridural catheter analgesia (PDA) is <strong>in</strong>creas<strong>in</strong>gly used postoperatively <strong>in</strong> major<br />
abdom<strong>in</strong>al surgery, <strong>in</strong>clud<strong>in</strong>g colon resections. The aim is not only to reduce postoperative pa<strong>in</strong> but<br />
also to facilitate convalescence, especially to allow early mobilisation. We compared postoperative<br />
outcome, <strong>in</strong> particular the number of footsteps, between patients with and without PDA.<br />
Methods: Between august 2007 and march 2008 data of patients undergo<strong>in</strong>g open colonic resection<br />
<strong>in</strong> a s<strong>in</strong>gle center were collected prospectively. Data (postoperative complications, hospital stay, stool<br />
passage, vomit<strong>in</strong>g) were extracted from hospital charts. All patients got a portable watch that counted<br />
all footsteps that a patient was perform<strong>in</strong>g over a 24 hour time period. Every 24 hours, the watch was<br />
read off and the footsteps were recorded. We separated all patients <strong>in</strong>to two groups, one with (group<br />
1; n=23, 64%) and one without PDA (group 2; 13, 36%). We <strong>in</strong>cluded 15 women and 21 men, with a<br />
median age of 69.5 years (range 31-88). Performed operations were: left hemicolectomy (n=11, 31%),<br />
right hemicolectomy (8, 22%), subtotal colectomy (5, 14%) and rectosigmoid resections (12, 33%).<br />
Results: Demographic data of group 1 and 2 are comparable. Vomit<strong>in</strong>g follow<strong>in</strong>g colonic operation<br />
occurred <strong>in</strong> 26.1% <strong>in</strong> group 1 and <strong>in</strong> 69.2% of patients <strong>in</strong> group 2 (p = 0.0168, Fisher’s Exact test). There<br />
was a trend to earlier first stool passage <strong>in</strong> group 1 than <strong>in</strong> group 2, 2.3 days and 2.9 days, respectively,<br />
but it didn’t reach significance (p = 0.2; t-test). For every s<strong>in</strong>gle day there was no significant difference<br />
between mean footsteps performed <strong>in</strong> the first five days after colonic surgery, they were 410 (SE 139;<br />
day 1), 771 (SE 330; d2), 1794 (SE 981; d3), 1465 (SE 553; d4) and 2651 (SE 933; d5) <strong>in</strong> group 1<br />
and 594 (SE 240; d1), 830 (SE 281; d2), 1559 (SE 379; d3), 2095 (SE 599; d4) and 2841 (SE 701;<br />
d5) <strong>in</strong> group. No significant differences were found for postoperative complications and for length of<br />
hospitalization.<br />
Conclusion: This prelim<strong>in</strong>ary data shows that cont<strong>in</strong>uous peridural catheter analgesia may be associated<br />
with earlier return<strong>in</strong>g of bowel function but not with premature mobilization. Because the patient<br />
collective is small and PDA is not randomly used, it has to be proven <strong>in</strong> a prospective randomized trial.<br />
99.11<br />
S<strong>in</strong>gle port access mesh repair of primary and <strong>in</strong>cisional ventral hernia: a step toward less parietal<br />
trauma<br />
P. Bucher, F. Pug<strong>in</strong>, Ph. Morel (Geneva)<br />
Objective: S<strong>in</strong>gle port access (SPA) laparoscopic surgery has rapidly entered cl<strong>in</strong>ical practice. SPA<br />
approach may be of <strong>in</strong>terest <strong>in</strong> patients prone to trocar port <strong>in</strong>cisional hernia. This reason may be one<br />
of the fundamentals for test<strong>in</strong>g this approach for ventral hernia repair. We here report a new technique<br />
of SPA ventral, either primary or <strong>in</strong>cisional, hernias mesh repair us<strong>in</strong>g work<strong>in</strong>g channel laparoscope<br />
and standard laparoscopic <strong>in</strong>struments.<br />
Methods: Prospective experience with SPA laparoscopic prosthetic repair of primary and <strong>in</strong>cisional<br />
ventral hernia <strong>in</strong> 45 patients. Patient’s median age was 46 years, 26-85, and BMI 30, 20-38 kg/m 2 .<br />
Mean fascial defect was 9.4 cm 2 for primary hernia (n=16) and18.4 cm 2 for <strong>in</strong>cisional hernia (n=18;<br />
one patient had comb<strong>in</strong>ed primary and <strong>in</strong>cisional hernias). Intraperitoneal composite mesh hernia<br />
repair were achieved through a 12mm flank port us<strong>in</strong>g conventional laparoscopic port. To complete<br />
surgeries work<strong>in</strong>g channel laparoscope were used with standard strait laparoscopic <strong>in</strong>struments.<br />
Meshes were fixed us<strong>in</strong>g resorbable tackers and trans-fascial stitches.<br />
Results: SPA laparoscopic repair of primary and <strong>in</strong>cisional ventral hernia was completed <strong>in</strong> all cases<br />
without conversion to standard laparoscopy. Median operative time was 58, 42-95 m<strong>in</strong>utes. No <strong>in</strong>traoperative<br />
or post-operative complications were recorded. Median hospital stay was 1 (1-5) days. No<br />
recurrence or trocar port site <strong>in</strong>cisional hernia have been recorded dur<strong>in</strong>g follow-up (median follow-up:<br />
12 ,19-1, months).<br />
Conclusion: SPA prosthetic repair of primary and <strong>in</strong>cisional ventral hernia is easily feasible and seems<br />
safe. It may offer cosmetic and recovery advantages compare to multiport laparoscopic repair. Ma<strong>in</strong><br />
<strong>in</strong>terest<strong>in</strong>gly, SPA ventral hernia repair decrease parietal trauma and scarr<strong>in</strong>g <strong>in</strong> patients at risk of trocar<br />
port site <strong>in</strong>cisional hernia and may be associated with a decrease <strong>in</strong> their rate compare to multiport<br />
laparoscopy. SPA ventral hernia repair has to be compared through randomized trial to standard<br />
laparoscopic approach.<br />
swiss <strong>knife</strong> 2010; 7: special edition 65