2008 Clinical Practice Guidelines - Canadian Diabetes Association

2008 CLINICAL PRACTICE GUIDELINES
S92
and yerba mate. It is important to be aware of the following
drug interactions: Hypericum perforata (St John’s wort) (used
in depression) induces CYP3A4 and can reduce levels of
statins cleared by this mechanism; Gingko biloba (used for
Alzheimer’s disease and intermittent claudication) reduces
platelet aggregation and can potentiate other medications
that affect bleeding; psyllium can retard the absorption of
some drugs and minerals.
For a more detailed discussion of CAM and diabetes, see
the review by Yeh and colleagues (62).
RECOMMENDATIONS
1. At this time, CAM is not recommended for glycemic
control for individuals with diabetes, as there is not
sufficient evidence regarding safety and efficacy
[Grade D, Consensus].
2. Individuals with diabetes should be routinely asked
if they are using CAM [Grade D, Consensus].
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