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2008 Clinical Practice Guidelines - Canadian Diabetes Association

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<strong>2008</strong> CLINICAL PRACTICE GUIDELINES<br />

S18<br />

A dosage of 850 mg BID for an average of 2.8 years significantly<br />

decreased progression to diabetes by 31%. In the DPP<br />

population, metformin did not have any significant effect in<br />

the older age group (≥60 years) and in less obese (body mass<br />

index [BMI]

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