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Research Publications - College of Medicine and Health Science

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Effect <strong>of</strong> tigerinin-1R from the Vietnamese common<br />

lowl<strong>and</strong> frog Hoplobatrachus rugulosus on plasma insulin<br />

concentrations in high fat-fed mice with dietary-induced<br />

obesity <strong>and</strong> insulin resistance. Glucose (18 mmol/kg body<br />

weight) was administered by intraperitoneal injection at<br />

the time indicated by the arrow, either alone (control) or in<br />

combination with tigerinin-1R (75 nmol/kg body weight). (A)<br />

Plasma insulin concentrations <strong>and</strong> (B) the integrated response<br />

(area under the curve, AUC) are shown. Values are mean ± SEM<br />

for six independent experiments. *P

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