Research Publications - College of Medicine and Health Science
Research Publications - College of Medicine and Health Science
Research Publications - College of Medicine and Health Science
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Department <strong>of</strong> Biochemistry<br />
18<br />
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Pr<strong>of</strong> JM Conlon [PI]<br />
Discovery <strong>and</strong> development <strong>of</strong><br />
peptide-based therapeutic agents<br />
for the treatment <strong>of</strong> patients with<br />
Type 2 diabetes mellitus.<br />
Pr<strong>of</strong> OMA El-Agnaf [PI]<br />
Developing a new therapeutic<br />
strategy for Parkinson’s disease<br />
<strong>and</strong> related disorders.<br />
Dr MJ Fern<strong>and</strong>ez-Cabezudo [CI]<br />
Inactivation <strong>of</strong> myeloid-derived<br />
suppressor cells as a novel target<br />
for enhancing. cancer immunotherapy<br />
Terry Fox Fund for Cancer <strong>Research</strong><br />
Grants<br />
Dr AH Al-Marzouqi [PI]<br />
Investigating the mechanisms <strong>of</strong><br />
action <strong>of</strong> the Snf2-homolog protein<br />
Fun30 (continuation).<br />
Pr<strong>of</strong> JM Conlon [PI]<br />
Transformation <strong>of</strong> the naturally<br />
occurring frog skin peptides<br />
ascaphin-8 <strong>and</strong> XT-7 into potent,<br />
non-toxic anti-cancer agents<br />
Pr<strong>of</strong> S Galadari [PI]<br />
Characterization <strong>of</strong> curcumin signal<br />
transduction <strong>and</strong> apoptosis as<br />
possible target for chemotherapy<br />
(continuation).<br />
Dr MJ Fern<strong>and</strong>ez-Cabezudo [PI]<br />
Novel resistance biomarkers in human<br />
breast cancer (continuation).<br />
Pr<strong>of</strong> H Raza [PI]<br />
Alterations in mitochondrial<br />
bioenergetics <strong>and</strong> glutathione<br />
metabolism by NSAIDs (non-steroidal<br />
anti-inflammatory drugs):<br />
implications in cancer prevention<br />
<strong>and</strong> treatment.<br />
Emirates Foundation Grants<br />
Dr AH Al-Marzouqi [PI]<br />
The Cooperation <strong>and</strong>/or Competition<br />
between the ATP-dependant<br />
Chromatin-Remodeling Protein<br />
SWI/SNF <strong>and</strong> the Histone Acetyltransferase<br />
SAGA in Binding to<br />
Nucleosomes (continuation)<br />
Pr<strong>of</strong> S Galadari [PI]<br />
Purification <strong>and</strong> characterization<br />
<strong>of</strong> a novel more hydrophobic<br />
is<strong>of</strong>orm <strong>of</strong> N-acylsphoingosine<br />
amidohydrolase (continuation)<br />
Michael J. Fox Foundation for<br />
Parkinson’s <strong>Research</strong>, USA<br />
Grants<br />
Pr<strong>of</strong> OMA El-Agnaf [PI]<br />
Validation <strong>of</strong> alpha-synuclein<br />
oligomers as biomarker for Parkinson’s<br />
disease.<br />
Pr<strong>of</strong> OMA El-Agnaf [PI] (with<br />
Parnetti L).<br />
Validation <strong>of</strong> lysosomal enzymes<br />
assay in CSF.<br />
Pr<strong>of</strong> OMA El-Agnaf [PI]<br />
Testing novel compounds for noninvasive<br />
delivery <strong>of</strong> small interfering<br />
RNA into CNS.<br />
Lundbeck Foundation, Denmark.<br />
Pr<strong>of</strong> OMA El-Agnaf [PI] (with Li J-Y<br />
<strong>and</strong> Hansen C).<br />
Can we block aggregation <strong>and</strong><br />
intercellular propagation <strong>of</strong> alphasynuclein<br />
to prevent pathological<br />
progression <strong>of</strong> Parkinson’s disease ?<br />
European Union Collaborative<br />
Project.<br />
Pr<strong>of</strong> OMA El-Agnaf [PI]<br />
European Project on Mendelian<br />
Forms <strong>of</strong> Parkinson’s Disease.<br />
(Continuation)<br />
Dubai Harvard Foundation for<br />
Medical <strong>Research</strong>, Dubai, UAE<br />
Dr AH Al-Marzouqi [PI]<br />
Biochemical characterization <strong>and</strong><br />
functional analysis <strong>of</strong> chromatin-<br />
remodeling proteins in gene<br />
activation <strong>and</strong> silencing (continuation).<br />
International Center for Genetic<br />
Engineering <strong>and</strong> Biotechnology<br />
(ICGEB)<br />
Dr AH Al-Marzouqi [PI]<br />
Studying chromatin-modifying<br />
proteins in transcription regulation<br />
(continuation).<br />
Sheikh Hamdan Award for<br />
Medical <strong>Science</strong>s<br />
Pr<strong>of</strong> S Galadari [PI]<br />
Investigation <strong>of</strong> signaling<br />
mechanisms <strong>of</strong> tumor suppressive<br />
sphingolipids<br />
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