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Research Publications - College of Medicine and Health Science

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Department<br />

<strong>of</strong> Obstetrics<br />

& Gynaecology<br />

<strong>Research</strong> Pr<strong>of</strong>ile<br />

The <strong>Research</strong> interests in the Department <strong>of</strong><br />

Obstetrics <strong>and</strong> Gynaecology are in Obstetrics,<br />

Fetal <strong>Medicine</strong>, Gynaecology, Oncology <strong>and</strong><br />

Urogynaecology.<br />

Dr. Hassan Elbiss’s major area <strong>of</strong> interests is<br />

urogyneacology, minimal access surgery, invitro<br />

human placenta perfusion.<br />

Dr. Hisham Mirghani’s major area <strong>of</strong> interest<br />

is fetal growth <strong>and</strong> physiology in diabetic<br />

pregnancy, fetal anomalies, in-vitro human<br />

placental perfusion.<br />

Pr<strong>of</strong>essor Mutairu Ezimokhai is interested in<br />

pathophysiology <strong>of</strong> pregnancy <strong>and</strong> medical<br />

disorders in pregnancy. Expertise is in<br />

working with vascular <strong>and</strong> uterine smooth<br />

muscles<br />

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placenta model<br />

The initial electron microscopic examination showed several<br />

ultrastructure changes.<br />

The syncytiotrophoblasts <strong>of</strong> normal placenta has numerous<br />

translucent cytoplasmic granules. These translucent granules<br />

were lost in the cytoplasm <strong>of</strong> syncytiotrophoblast in placentas <strong>of</strong><br />

diabetic patients. In addition, the chorionic villi in diabetic subject<br />

contain more discrete bundles <strong>of</strong> collagen fibers compared<br />

to control (Figure 1: a; control, b; diabetic)<br />

Figure 2 (a;control, b;diabetic) shows the syncytiotrophoblast <strong>of</strong><br />

the placenta <strong>of</strong> control <strong>and</strong> diabetic subjects. These cells contain<br />

Associate Pr<strong>of</strong>essor<br />

& Acting Chair:<br />

Dr. Hisham Mirghani<br />

Pr<strong>of</strong>essor:<br />

Pr<strong>of</strong> Mutairu Ezimokhai<br />

Assistant Pr<strong>of</strong>essor:<br />

Dr. Hassan Elbiss<br />

Medical <strong>Research</strong><br />

Specialist:<br />

Dr. Nawal Osman<br />

Flora D. Lone<br />

Medical Secretary:<br />

Clarina G. Garcia<br />

51

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