Research Publications - College of Medicine and Health Science

describe inflammatory phenotypes in induced
sputum in children with asthma. Airway inflammation
is a marker of asthma severity and
response to treatment.
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patients. The aim of this study to determine the
prevalence of Fabry disease in UAE.
NEPHROLOGY (H. Narchi)
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tubular damage in young children with uri-
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G Dhatt) The association of the presence,
magnitude and duration of these markers as a
potential predictor for permanent renal cortical
scarring will be looked into. The results might
potentially identify, without the risk of ionizing
radiations, those children at higher risk
of scarring who will need long0term antibiotic
prophylaxis and other uro-imaging studies.
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fever versus experimental nephrotic
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marked difference in the pattern of cytokines
excretion. This would allow differentiation
between the benign proteinuria associated with
febrile illnesses in nephrotic children, versus the
onset of a relapse of nephritic syndrome where
prolonged corticosteroid therapy would be
required, with potential requirement for renal
biopsy and cytotoxic or immunosupooressive
therapy.
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is being planned
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that, when diagnosed in the third trimester of
pregnancy, it has a higher predictive power for
underlying uropathies. These results will result
in modifications of current guidelines.
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to antibiotics in children with urinary tract
infections (H. Narchi, M. Hamdani) have looked
at the role of first versus recurrent infection,
presence of vesico-ureteric reflux and prior antibiotic
prophylaxis. The results have implications
for clinical practice.
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Al Suwaidi)
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C, seroepidemiology and neonatal screening
of CMV and other congenital infections.
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Diseases.
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(Y. Abdulrazzaq).
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first standards for assessing intrauterine and
postnatal physical growth of UAE newly born
infants and children. Role of food allergy and
airway reactivity is another area of interest in
our department. This is being investigated in a
population based approach.
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����������������������������������������������vascular
diseases the research activities in our
department is involved in the study of the
Cardiovascular Diseases Risk Factors in Emirates
adolescents and young patients (age
between 15 – 25 year-old) with type 1 and type
2 Diabetes Mellitus. The hypothesis is to find out
that the microalbuminuria may correlate with
endothelial dysfunction and cardiovascular autonomic
neuropathy in adolescents and young
adults. Young patients with T1DM and T2DM
that carry the high risk haptoglobin 2 allele
would have higher levels of oxidative stress and
more diabetes complications.
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(PUFAs) on Left Ventricular Function and
Coronary Flow (CF) in Children with Type 1
Diabetes Mellitus. Young diabetics are at risk of
developing diabetic cardiomyopathy. Coronary
flow disturbance is suggestive of coronary
microvascular dysfunction, which is the earliest
manifestation of coronary heart disease (CHD).
The interaction between inflammation and the
adaptive immune system are the mechanistic
link for the pathogenesis of Type 1 DM and its
complications. Coronary flow disturbance could
be secondary to inflammation and endothelial
dysfunction. Improvement of endothelial
dysfunction would favourably influence the
clinical prognosis. PUFAs reduce the inflammatory
processes, vasoconstriction, and platelets
aggregation, all known to be anti-atherogenic.
Department of Paediatrics
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