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Protocolo de Actuación en Mieloma múltiple - Sociedad Asturiana ...

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14. Palumbo A, Bringh<strong>en</strong> S, Caravita T, et al. Italian Multiple<br />

Myeloma Network, GIMEMA. Oral melphalan and prednisone chemotherapy plus<br />

thalidomi<strong>de</strong> compared with melphalan and prednisone alone in el<strong>de</strong>rly pati<strong>en</strong>ts with multiple<br />

myeloma: randomised controlled trial. Lancet 2006;11: 825-31<br />

15. Palumbo A, Bringh<strong>en</strong> S, Cavalli M et al. Bortezomib, Melphalan, Prednisone and<br />

Thalidomi<strong>de</strong> Followed by Maint<strong>en</strong>ance with Bortezomib and Thalidomi<strong>de</strong> (VMPT-VT) for<br />

Initial Treatm<strong>en</strong>t of El<strong>de</strong>rly Multiple Myeloma Pati<strong>en</strong>ts: Updated Follow-up and Impact of<br />

Prognostic Factors. Blood 2010; 116 (abst. 620)<br />

16. Palumbo A, Z<strong>de</strong>nek A, Kropff et al. A phase 3 study evaluating the efficacy and safety of<br />

l<strong>en</strong>alidomi<strong>de</strong> combined melphalan and prednisone followed by continous l<strong>en</strong>alidomi<strong>de</strong><br />

maint<strong>en</strong>ance (MPR-R) in pati<strong>en</strong>ts ≥ 65 years with newly diagnosed multiple myeloma: Update<br />

results for aged 65-75 years <strong>en</strong>rolled in MM-015. Blood 2011; 118 (abst.475)<br />

17. Palumbo A, An<strong>de</strong>rson K. Multiple Myeloma. N Engl J Med 2011; 364: 1046-60<br />

18. Palumbo A, Bringh<strong>en</strong> S, Ludwig H et al. Personalized therapy in multiple myeloma according<br />

to pati<strong>en</strong>t age and vulnerability: a report of the European Myeloma Network (EMN). Blood<br />

2011; 118: 4519-4529<br />

19. Pönisch W, Mitrou PS, Merkle K, Herold M, Assmann M, Wilhelm G, Dachselt K, Richter P,<br />

Schirmer V, Schulze A, Subert R, Harksel B, Grobe N, Stelzer E, Schulze M, Bittrich A,<br />

Freund M, Pasold R, Friedrich T, Helbig W, Nie<strong>de</strong>rwieser D. Treatm<strong>en</strong>t of b<strong>en</strong>damustine and<br />

prednisone in pati<strong>en</strong>ts with newly diagnosed multiple myeloma results in superior complete<br />

response rate, prolonged time to treatm<strong>en</strong>t failure and improved quality of life compared to<br />

treatm<strong>en</strong>t with melphalan and prednisone--a randomized phase III study of the East German<br />

Study Group of Hematology and Oncology (OSHO). J Cancer Res Clin Oncol. 2006;<br />

132(4):205-12<br />

20. Rajkumar SV, Jacobus S, Callan<strong>de</strong>r N et al. L<strong>en</strong>alidomi<strong>de</strong> plus high dose <strong>de</strong>xametasona vs<br />

l<strong>en</strong>alidomi<strong>de</strong> plus low dose <strong>de</strong>xametasona as initial therapy for newly diagnosed multiple<br />

myeloma: an oplel-label randomised controlled trial. Lancet Oncol 2010; 11: 29-37<br />

21. San Miguel JF, Schlag R, Khuageva NK, Dimopoulos MA, Shpilberg O, Kropff M, Spicka I,<br />

Petrucci MT, Palumbo A, Samoilova OS, Dmoszynska A, Abdulkadyrov KM, Schots R, Jiang<br />

B, Mateos MV, An<strong>de</strong>rson KC, Esseltine DL, Liu K, Cakana A, van <strong>de</strong> Vel<strong>de</strong> H, Richardson<br />

PG; VISTA Trial Investigators. Bortezomib plus melphalan and prednisone for initial<br />

treatm<strong>en</strong>t of multiple myeloma. N Engl J Med. 2008; 359(9):906-17<br />

22. San Miguel JM, Schlag R, Khuageva N et al. VMP vs MP in pati<strong>en</strong>ts with previously<br />

untreated multiple myeloma and no increased risk of second primary malignancies: Final<br />

results of the phase 3 VISTA trial. Blood 2011; 118 (abst.476)<br />

23. Vesole DH, Jacobus S, Rajkumar SV et al. L<strong>en</strong>alidomi<strong>de</strong> plus lose doses <strong>de</strong>xametasone<br />

superior one and two year survival regardless of age compared to l<strong>en</strong>alidomi<strong>de</strong> plus highdoses<br />

<strong>de</strong>xametasone. Blood 2010; 116. (abst. 308)<br />

24. Wijermans, Schaafsma M, van Nor<strong>de</strong>n Y, Ammerlaan R, Wittebol S, Sinnige H el al.<br />

Melphalan+prednisone versus Melphalan+prednisone+thalidomi<strong>de</strong> in induction therapy for<br />

multiple myeloma in el<strong>de</strong>rly pati<strong>en</strong>ts: Final analysis of the Dutch cooperative Group HOVON<br />

49 study. Blood 2008; 112 (abst.649)<br />

Grupo Asturiano <strong>de</strong> Linfoma y <strong>Mieloma</strong><br />

54

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