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Vol. 5, n. 1, January-March 2009 1th International ... - Salute per tutti

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18<br />

A. Sparavigna, B. Tenconi, I. De Ponti<br />

ucts gave an increment of hydration corresponding<br />

to 18% for D i s p a r i c ream and to 22%<br />

for P a r i c ream.<br />

Microrelief surface evaluation<br />

Although this evaluation, <strong>per</strong>formed<br />

at T8, did not show a statistical significant variation<br />

of cutaneous surface microrelief regularity,<br />

a tendencial regularizing activity of the treatment<br />

on skin microrelief (+5%) was found.<br />

Self-evaluation questionnaire<br />

The overall activity of the treatment<br />

on striae was self <strong>per</strong>ceived by the participating<br />

subjects in 72% of cases.<br />

C onclusions<br />

It is common clinical ex<strong>per</strong>ience that<br />

topical treatment of stretchmarks is hardly successful<br />

especially for old lesions, which can be<br />

considered as scars caused by distension and<br />

rupture of dermal fibres. On the contrary, striae<br />

of recent onset may undergo spontaneous resolution.<br />

The combined treatment under study<br />

was able to provide a stimulus to fibroblasts in<br />

the dermis as well as an improved epidermal<br />

turnover. Instrumental measurements of striae<br />

deepness and skin elasticity, clinical evaluations<br />

and self evaluation questionnaire provided statistically<br />

significant results, especially for striae<br />

dating more than two years.<br />

L ectures<br />

Khanna S, Venojarvi M, Roy S, Sharma N,<br />

Trikha P, Bagchi D, Bagchi M, Sen CK. Dermal wound healing<br />

pro<strong>per</strong>ties of redox-active grape seed proanthocyanidins.<br />

Free Radic Biol Med 2002; 33:1089-96.<br />

Baliga MS, Katiyar SK. Chemoprevention of photocarcinogenesis<br />

by selected dietary botanicals. Photochem Photobiol<br />

Sci 2006; 5:243-53.<br />

Lee AR. Enhancing dermal matrix regeneration and biomechanical<br />

pro<strong>per</strong>ties of 2nd degree-burn wounds by EGFimpregnated<br />

collagen sponge dressing. Arch Pharm Res<br />

2005; 28:1311-6.<br />

Carter K. Growth factors: the wound healing therapy of the<br />

f u t u re. Br J Community Nurs 2003; 8:S15-6, S18-9, S22-3.<br />

Bhora FY, Dunkin BJ, Batzri S, Aly HM, Bass BL, Sidawy AN,<br />

H a rmon JW. Effect of growth factors on cell proliferation and<br />

epithelialization in human skin. J Surg Res 2005; 59:236-44.<br />

Journal of Plastic Dermatology <strong>2009</strong>; 5, 1<br />

Thapa BR. Health factors in colostrum. Indian J Pediatr<br />

2005; 72:849-52.<br />

Zhang YQ. Applications of natural silk protein sericin in<br />

biomaterials. Biotechnol Adv 2002; 20:91-100.<br />

Minoura N, Aiba S, Gotoh Y, Tsukada M, Imai Y.<br />

Attachment and growth of cultured fibroblast cells on silk<br />

protein matrices. J Biomed Mater Res 1995; 29:1215-21.<br />

Corcuff P, Chatenay F, Leveque JL. A fully automated system<br />

to study skin surface patterns. Int J Cosm Sci 1984,<br />

6:167-186.<br />

De Rigal J, Leveque JL. In vivo measurement of the stratum<br />

c o rneum elasticity. Bioengineering and the skin 1985; 1:13-23.<br />

Elsner P., Berardesca E., Maibach H. Bioengineering of the<br />

skin: Water and the stratum corneum. CRC Press, Boca<br />

Raton, 1994.<br />

F e rn a y, Vo l t a i re. The World Medical Association “Wo r l d<br />

Medical Association Declaration of Helsinki”, Hong-Kong,<br />

1 9 8 9 .<br />

Hoppe U, Sauermann G, Lunderstadt R. Quantitative<br />

analysis of the skin surface by means of digital signal processing.<br />

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ICH Harmonised Tripartite Guideline - Guideline for Good<br />

Clinical Practice. <strong>International</strong> Conference on<br />

Harmonisation of Technical Requirements for Registration<br />

of Pharmaceuticals for Human Use, 1996.<br />

Mitts T, Jimenez F, Hinek A. Skin biopsy analysis reveals<br />

predisposition to stretchmark formation. Aesthetic Surgery<br />

Journal, 2005; 25:593-600.<br />

Prall JK. The effectiveness of cosmetic products in alleviating<br />

a range skin dryness conditions as determined by clinical<br />

and instrumental techniques. <strong>International</strong> Journal of<br />

Cosmetic Science 1986; 8:159-174.<br />

Sachs L. Applied statistics: a handbook of techniques.<br />

Heidelberg: Springer, 1981; 536-539.<br />

Salter DC et al. Skin mechanics measured in vivo using torsion:<br />

a new and accurate model more sensitive to age, sex<br />

and moisturizing treatment. Preprints 17t h I F S C C<br />

<strong>International</strong> Congress Yokohama 1992; 758-780.<br />

Setaro M., Sparavigna A. Morphological Evaluation of Skin<br />

Surface by Fourier’s Transform: A Study on the Phase and<br />

the Modulus” Preprints of 12th <strong>International</strong> Symposium<br />

on Bioengineering and the Skin, Boston 1998.<br />

Setaro M., Sparavigna A. Irregularity skin index (ISI): a<br />

tool to evaluate skin surface texture. Skin Research and<br />

Technology 2001; 7:159-163.<br />

Sparavigna A., Setaro M. Misurazione delle proprietà meccaniche<br />

della cute mediante metodi di torsione. In:<br />

“Diagnostica non invasiva in dermatologia”. A cura di<br />

Stefania Seidenari, EDRA. Medical Publishing & New<br />

Media, Milano, 1998, pp 323-328.<br />

Wilhelm KP, Elsner P, Berardesca E, Maibach HI.<br />

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Boca Raton: CRC Press 1997.

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