instit.oncol.cluj-napoca- sectia hematologie - 2012
instit.oncol.cluj-napoca- sectia hematologie - 2012
instit.oncol.cluj-napoca- sectia hematologie - 2012
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10.3.5 Tratamentul HCL varianta<br />
1. Analogi de purine – Cladribina, Pentostatina in dozele de mai sus<br />
2. Splenectomia<br />
3. Rituximab: 375 mg/m 2 /sapt 4 - 12<br />
4. Clorambucil: 3 – 6 mg/m 2 /zi x 1: 3 – 6 saptamani (in medie 4-10 mg/zi)<br />
BIBLIOGRAFIE<br />
1. Grever MR. How I Treat Hairy Cell Leukemia. Blood, 2010, 115: 21-28<br />
2. Tiacci E, Trifonov V, Schiavoni et al. BRAF mutations in hairy-cell leukemia.<br />
2011, 364(24):2305-15<br />
3. Petrov L, Cucuianu A, Bojan A, Urian L. Hematologie Clinica. Casa Cartii de Stiinta Cluj, 2009<br />
4. Robak T. Management of hairy cell leukemia variant. Leuk Lymphoma, 2011;52 Suppl 2:53-6.
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