The Principles of Clinical Cytogenetics - Extra Materials - Springer

Index 571
Familial rearrangements, 168–169, 170,
f170, 171, 178, 180, 183, 185,
191–193, f192, 195, 196, 199, 200
FANC genes, 351
Fanconi anemia, 5, 350–351, f352, 550
FBS, 65
FDA, 94, 108
Fecundity, 323-324
Femur, short
and racial variation, 299
and trisomy 21, 299, t303
Fertilization errors, 334
diandry, 334
digyny, 334
dispermy, 334-336
molar pregnancy, 334–336
FES, 406
Fetal bovine serum (FBS), 65
FGFR1, 375, 406
FHKR-PAX, t422, 428–429
Fiber FISH, 481–482
Fibromatosis, 431
Fibrosarcoma, 431–432
Field diaphragm, f82, 83
Filters
interference, 83
brightfield microscopy, 81–83
dichroic mirror, 89
dual or multi-band emission, 89–90
emission, 89
excitation, 89
fluorescent, 89
infra red (IR), 89
neutral density (ND), 89, 90
single emission, 89–90
Filter wheel, motorized, 125, f127
Final reports, 103, 104
First trimester maternal serum screening,
553, 554
FISH (see also hybridization, in situ and
fluorescence in situ hybridization),
74
FISH probe labeling, 457
Fixative, 114
FKHR, 476
FL1, 476
Flow cytometry (for products of
conception), 338
FLT3, 380, 385
Fluorescence in situ hybridization
(FISH), 74, 133, 134, 168, 175,
178, f180, 183, f184, 186, 188,
200, 547, 549, 550, 553
and amniocentesis, 272
and maternal cell contamination, 312
and mosaic trisomy 16, 310
comparative genomic hybridization
(CGH), 126, 168, 251, 338–339,
480, f481
duplication, 462, f463
for products of conception, 329–330,
338, 341
instrumentation for, 117, 118, f118,
f119
hybridization, 118, 119
pretreatment, 118
marker chromosome, 462–464, t464,
f465
methods, 455–458, f456
microdeletion, 458
microduplication, 458
multi-color FISH (M-FISH), 462
preimplantation genetic diagnosis
(PGD), 466
prenatal, 464–466, f466, t466
probes, 455–457
subtelomeric abnormalities, 459–462,
f461
Fluorescence microscopy, 89–91, f90
FMR1, t251, 498, 500–503
definition of, 500
homologous genes, 500
FMR2, 498, 506–507
FMRP, 500–502, 506
Folate-sensitive fragile sites, 495, t496,
497, t499
Folate-sensitive autosomal rare fragile
sites (ARFSs), 350
Folic acid (and neural tube defects), 305