Inhibitor SourceBook™ Second Edition

Phosphorylation/Dephosphorylation
Protein Phosphatase Inhibitors, continued
Product Cat. No. Comments Size Price
Sodium Stibogluconate 567565 (Antimony Sodium Gluconate; NaSb v ; SSG)
An irreversible inhibitor of (PTPase), including Src homology PTPase- (SHP- ). Exhibits
anti-leishmanial properties. At higher concentrations, inhibits SHP-2 and PTP B activities.
Suramin, Sodium Salt 574625 Useful as a reversible and competitive inhibitor of protein tyrosine phosphatases. 50 mg
200 mg
N InSolution
Tautomycetin, S.
griseochromogenes
N
Tautomycin,
Streptomyces
spiroverticillatus
Phosphatase Inhibitor Cocktail Set I
A cocktail of three phosphatase inhibitors that will inhibit alkaline
phosphatases as well as serine/threonine protein phosphatases such
as PP and PP2A. This product is provided as a set of five ml vials.
Each vial contains ml of phosphatase inhibitor cocktail solubilized
in DMSO with the following components: Bromotetramisole oxalate
(0.5 mM), Cantharidin (Cat. No. 2 0 55; 500 mM), and Microcystin-
LR (Cat. No. 4758 5; 500 nM). Not available for sale outside the
United States.
Cat. No. 524624 1 set $170
Phosphatase Inhibitor Cocktail Set II
A cocktail of five phosphatase inhibitors for the inhibition of acid
and alkaline phosphatases as well as protein tyrosine phosphatases
(PTPs). Suitable for use with tissue and cell extracts, including
extracts containing detergents. Provided as a set of five vials, with
each vial containing ml aqueous solution of 200 mM Imidazole,
00 mM Sodium Fluoride, 5 mM Sodium Molybdate, 00 mM
Sodium Orthovanadate, and 400 mM Sodium Tartrate Dihydrate.
Cat. No. 524625 1 set $213
Phosphatase Inhibitor Cocktail Set III
580550 A mM (50 mg/82 ml) solution of Tautomycetin in DMSO. Specifically inhibits PP
activity with ~38-fold greater selectivity over PP2A (IC 50 = .6 nM for PP and 62 nM
for PP2A). Further, inhibits PP5 at higher concentrations (IC 50 ~ mM) and only weakly
affects calcineurin and LDP- at mM.
580551 A potent inhibitor of PP (IC 50 = nM), PP2A (IC 50 = 0 nM), and smooth muscle
endogenous phosphatase (IC 50 = 6 nM).
A cocktail of four phosphatase inhibitors for the inhibition of both
serine/threonine and protein tyrosine phosphatases. Available as a
ml vial or as a set of five ml vials. Each vial contains ml
of aqueous solution with the following components: 50 mM
Sodium Fluoride, 0 mM b-Glycerophosphate, 0 mM Sodium
Pyrophosphate Decahydrate, and mM Sodium Orthovanadate.
Cat. No. 524627 1 ml
1 set
$115
$395
Phosphatase Inhibitor Cocktail Set IV
Phosphotyrosine Phosphatase Inhibitor Set
(Vanadium)
Contains 5 g of Sodium Orthovanadate (Cat. No. 567540),
0 mg each of bpV(phen) (Cat. No. 203695) and mpV(pic)
(Cat. No. 475950).
Cat. No. 525325 1 set $203
Protein Phosphatase Inhibitor Set II
g $75
Contains 0 mg Cypermethrin (Cat. No, 239900), mg Dephostatin
(Cat. No. 263200), 0 mg Okadaic Acid (Cat. No. 495604), and mg
NIPP- , Bovine Thymus.
Cat. No. 539630 1 set $304
62 Orders Phone 800 854 34 7
Calbiochem • Inhibitor SourceBook
Fax 800 776 0999
Web www.emdbiosciences.com/calbiochem
N
$34
$
50 mg $ 80
50 mg $2 7
A cocktail of three phosphatase inhibitors for the inhibition of both
serine/threonine and alkaline phosphatases. Available as a ml vial
or as a set of five ml vials. Each vial contains ml of solution with
the following components: 500 mM Cantharidin (Cat. No. 2 0 55),
2.5 mM (-)-p-Bromotetramisole oxalate, and mM Calyculin A,
Discodermia calyx (Cat. No. 20885 ).
Cat. No. 524628 1 ml
1 set
$75
$285