Inhibitor SourceBook™ Second Edition
Inhibitor SourceBook™ Second Edition
Inhibitor SourceBook™ Second Edition
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Apoptosis<br />
Caspase <strong>Inhibitor</strong>s<br />
Product Cat. No. Sequence<br />
Cell -<br />
Permeable<br />
Reversible?<br />
Known Target<br />
Caspases<br />
(or Granzyme B)<br />
Size Price<br />
Caspase <strong>Inhibitor</strong> I 627610 Z-VAD(OMe)-FMK a Yes No General mg $ 84<br />
InSolution Caspase <strong>Inhibitor</strong> I 627609 Z-VAD(OMe)-FMK a Yes No General mg $ 84<br />
Caspase <strong>Inhibitor</strong> I, Biotin Conjugate 218742 Biotin-X-VAD(OMe)-FMK a — No General mg $355<br />
Caspase <strong>Inhibitor</strong> II 218735 Ac-VAD-CHO ‡ No Yes General mg $65<br />
Caspase <strong>Inhibitor</strong> II,<br />
Cell-Permeable<br />
218830 Ac-AAVALLPAVLLALLAPVAD-<br />
CHO<br />
Yes Yes General mg $ 64<br />
Caspase <strong>Inhibitor</strong> III 218745 Boc-D(OMe)-FMK a Yes No General 250 mg<br />
mg<br />
Caspase <strong>Inhibitor</strong> IV 218784 Boc-D(OBzl)-CMK b Yes No General 5 mg $60<br />
Caspase <strong>Inhibitor</strong> VI 219007 Z-VAD-FMK a — No General 250 mg<br />
mg<br />
N InSolution Caspase <strong>Inhibitor</strong> VI 219011 Z-VAD-FMK a — No General mg $ 82<br />
Caspase <strong>Inhibitor</strong> VIII 218729 Ac-VDVAD-CHO No Yes 2, 3, 7 mg $99<br />
N Caspase <strong>Inhibitor</strong> X 218723 — No Yes 3, 7, 8 5 mg $ 8<br />
Caspase <strong>Inhibitor</strong>, Negative Control 342000 Z-FA-FMK Yes No mg<br />
5 mg<br />
Caspase- <strong>Inhibitor</strong> I 400010 Ac-YVAD-CHO ‡ No Yes , 4 mg<br />
5 mg<br />
Caspase- <strong>Inhibitor</strong> I,<br />
Cell-Permeable<br />
400011 Ac-AAVALLPAVLLALLAP-<br />
YVAD-CHO<br />
64 Orders Phone 800 854 34 7<br />
Calbiochem • <strong>Inhibitor</strong> SourceBook<br />
Fax 800 776 0999<br />
Web www.emdbiosciences.com/calbiochem<br />
$57<br />
$ 44<br />
$62<br />
$ 82<br />
$77<br />
$3 3<br />
$60<br />
$243<br />
Yes Yes , 4 mg $ 70<br />
Caspase- <strong>Inhibitor</strong> II 400012 Ac-YVAD-CMK b Yes No , 4 5 mg $208<br />
Caspase- <strong>Inhibitor</strong> II, Biotin<br />
Conjugate<br />
400022 Biotin-YVAD-CMK b — No , 4 5 mg $297<br />
Caspase- <strong>Inhibitor</strong> IV 400015 Ac-YVAD-AOM d Yes No , 4 mg $95<br />
Caspase- <strong>Inhibitor</strong> V 400019 Z-Asp-CH 2 -DCB e Yes No , 4 5 mg $362<br />
Caspase- <strong>Inhibitor</strong> VI 218746 Z-YVAD(OMe)-FMK a Yes No , 4 250 mg<br />
mg<br />
Caspase-2 <strong>Inhibitor</strong> I 218744 Z-VD(OMe)VAD(OMe)-FMK a Yes No 2 250 mg<br />
mg<br />
Caspase-2 <strong>Inhibitor</strong> II 218814 Ac-LDESD-CHO No Yes 2, 3 mg<br />
5 mg<br />
Caspase-3 <strong>Inhibitor</strong> I 235420 Ac-DEVD-CHO ‡ No Yes 3, 6, 7, 8, 0 mg<br />
5 mg<br />
Caspase-3 <strong>Inhibitor</strong> I, Biotin<br />
Conjugate<br />
Caspase-3 <strong>Inhibitor</strong> I,<br />
Cell-Permeable<br />
InSolution Caspase-3 <strong>Inhibitor</strong> I,<br />
Cell-Permeable<br />
$88<br />
$263<br />
$<br />
$3 0<br />
$73<br />
$286<br />
$68<br />
$267<br />
235422 Biotin-DEVD-CHO ‡ — Yes 3, 6, 7, 8, 0 mg $ 7<br />
235423 Ac-AAVALLPAVLLALLAP-<br />
DEVD-CHO<br />
235427 Ac-AAVALLPAVLLALLAP-<br />
DEVD-CHO<br />
Caspase-3 <strong>Inhibitor</strong> II 264155 Z-D(OMe)E(OMe)VD(OMe)-<br />
FMK a<br />
InSolution Caspase-3 <strong>Inhibitor</strong> II 264156 Ac-AAVALLPAVLLALLAP-<br />
DEVD-CHO<br />
Caspase-3 <strong>Inhibitor</strong> II, Biotin<br />
Conjugate<br />
218747 Biotin-X-<br />
D(OMe)E(OMe)VD(OMe)-<br />
FMK a<br />
Yes Yes 3, 6, 7, 8, 0 mg $ 56<br />
Yes Yes 3, 6, 7, 8, 0 mg $ 56<br />
Yes No 3, 6, 7, 8, 0 250 mg<br />
mg<br />
$8<br />
$227<br />
Yes Yes 3, 6, 7, 8, 0 250 mg $83<br />
— No 3, 6, 7, 0 mg $366<br />
Caspase-3 <strong>Inhibitor</strong> III 218750 Ac-DEVD-CMK b Yes No 3, 6, 7, 8, 0 mg<br />
5 mg<br />
Caspase-3 <strong>Inhibitor</strong> IV 235421 Ac-DMQD-CHO ‡ No Yes 3 mg<br />
5 mg<br />
Caspase-3 <strong>Inhibitor</strong> V 219002 Z-D(OMe)QMD(OMe)-FMK Yes No 3 mg $238<br />
Key: a: FMK = Fluoromethyl ketone; b: CMK = Chloromethyl ketone; c: FAOM = 2,6-bis(trifluoromethyl) benzoyloxymethyl ketone; d: AOM = 2,6dimethylbenzoyloxy<br />
ketone; e: DCB = 2,6 dichlorobenzoyloxy; ‡: These aldehyde-based inhibitors may be cell-permeable, albeit to a lesser extent.<br />
$66<br />
$26<br />
$83<br />
$275