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Statistical Methods in Medical Research 4ed

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y<br />

y<br />

(a) L<strong>in</strong>ear<br />

p = 1<br />

(c) Cubic<br />

p = 3<br />

Fig. 12.1 Illustrations of polynomials of up to the fourth degree.<br />

x<br />

x<br />

y<br />

y<br />

(b) Quadratic<br />

p = 2<br />

(d) Quartic<br />

p = 4<br />

Note that, with n observations, all with different values of x, a polynomial of<br />

degree p ˆ n 1 would have n p 1 ˆ n …n 1† 1 ˆ 0 DF. It is<br />

always possible to fit a polynomial of degree n 1, so as to pass through n<br />

po<strong>in</strong>ts with different values of x, just as a straight l<strong>in</strong>e (p ˆ 1) can be drawn<br />

through any two po<strong>in</strong>ts. The Residual SSq is, therefore, also zero, and no<br />

significance tests are possible. To provide a test of the adequacy of the model,<br />

the degree of the polynomial should be considerably lower than the number of<br />

observations.<br />

Example 12.1<br />

12.1 Polynomial regression 379<br />

Table 12.1 gives the population size of England and Wales (<strong>in</strong> millions) as recorded at<br />

decennial censuses between 1801 and 1971; there is a gap <strong>in</strong> the series at 1941, as no census<br />

was taken <strong>in</strong> that year. It is of some <strong>in</strong>terest to fit a smooth curve to the trend <strong>in</strong><br />

population size, first, to provide estimates for <strong>in</strong>termediate years and, secondly, for<br />

projection beyond the end of the series, although demographers would <strong>in</strong> practice use<br />

more sophisticated methods of projection. The figure for 1981 is given at the foot of the<br />

ma<strong>in</strong> series to provide a comparison with estimates obta<strong>in</strong>ed by extrapolation from<br />

the ma<strong>in</strong> series.<br />

x<br />

x

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