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Aanesthetic Agents for Day Surgery - NIHR Health Technology ...

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TABLE 68 contd Summary of adult patient-based outcomes studies<br />

© Queen’s Printer and Controller of HMSO 2002. All rights reserved.<br />

<strong>Health</strong> <strong>Technology</strong> Assessment 2002; Vol. 6: No. 30<br />

Study Investigations Outcome Results Conclusions and Reviewers’ comments<br />

and subjects measures grade of evidence<br />

Larsen et al., (1) Propofol PAT Significant difference Found that PAT has the Part II is grade I; Part 1 is<br />

1992, 89 Sweden induction, (p < 0.05) in psychomotor following features: (1) experimenting with PAT<br />

propofol + O2 recovery of PAT between shallow learning curve;<br />

Two-part study: maintenance propofol group and (2) consistent and If the PAT is validated and<br />

I, experiment (15 patients) control group; no reproducible; (3) reliable, it has shown that<br />

on outcome significant difference in phenomenon of ‘arousal’ psychomotor recovery<br />

measures; II, (2) Propofol psychomotor recovery on has not been noticed; following isoflurane<br />

RCT induction, PAT between isoflurane (4) simple and easy to anaesthesia is quicker than<br />

isoflurane 5–2% and control; change in use. Found, using this that following propofol<br />

maintenance choice reaction time – PAT, that psychomotor infusion. Further studies are<br />

(15 patients) difference between recovery following required to evaluate the<br />

isoflurane (p < 0.05) and isoflurane anaesthesia precise difference between<br />

(3) Control propofol (p < 0.01) groups is quicker than that PAT-60 and PAT-200<br />

group: 15 compared with control following propofol<br />

unanaesthetised<br />

volunteers<br />

in PAT-60 infusion<br />

Law, 1997, 185<br />

(1) Assess Telephone Nursing care: excellent Patients on hold Grade IV<br />

UK usefulness of survey 76.3%; satisfactory 23.6%. were happy with new<br />

preoperative Advice leaflets: excellent day-surgery service; Patient satisfaction was<br />

Descriptive assessment No real 57.8%, satisfactory 42.1%. allocation of difficult to measure;<br />

study (telephone outcome Doctor waiting times preoperative questions on patient<br />

survey audit) (2) Identify measures of 5–180 min; 50% waited assessment time satisfaction were closed<br />

written and quality of life 30 min; mean waiting time should be realistic questions with a rating of<br />

verbal advice measures used 56.97 min (median 30 min). poor, fair, etc. Sample size<br />

26.3% (10) said they would was small<br />

(3) Identify Rating: poor, fair, prefer a longer stay<br />

usefulness of satisfactory, in hospital<br />

counselling<br />

criteria<br />

excellent<br />

(4) Assess<br />

patient satisfaction<br />

45 patients<br />

approached,<br />

38 participated<br />

(84.4%)<br />

Leith et al., Questionnaire Questions only 97.8% used NSAIDs; most Pain problems are a Grade IV<br />

1994, 19<br />

survey looking using diclofenac; 61.7% cause <strong>for</strong> concern in<br />

England and at: using ketorolac, about 70% of units. Questionnaire survey<br />

Wales administered either The authors believe<br />

(1) use of i.m. or i.v. that droperidol should Looking at practices in<br />

Descriptive analgesics not be used in day different day-surgery units<br />

survey postoperatively 90.8% supplied patients surgery. Prophylactic<br />

with analgesic drugs to anti-emetic drugs were<br />

(2) use of take home. 53.9% gave given in 53.9% of units<br />

prophylactic prophylactic anti-emetic<br />

anti-emetics drugs: metoclopramide<br />

46.1%; ondansetron 9.2%;<br />

231 units; droperiodol 28.4%;<br />

147 replied prochlorperazine 17.7%.<br />

(64%) Pain was considered a<br />

problem in 69.5%; 44%<br />

felt nausea was a problem<br />

continued<br />

153

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