Aanesthetic Agents for Day Surgery - NIHR Health Technology ...
Aanesthetic Agents for Day Surgery - NIHR Health Technology ...
Aanesthetic Agents for Day Surgery - NIHR Health Technology ...
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TABLE 71 contd Quality of cost or economic comparisons of anaesthetic agents<br />
© Queen’s Printer and Controller of HMSO 2002. All rights reserved.<br />
<strong>Health</strong> <strong>Technology</strong> Assessment 2002; Vol. 6: No. 30<br />
Study Study design Resources measured and costed Source of costs Results<br />
Data collection Economic checklist<br />
Kain et al., 1994, 215<br />
Source: RCT Study design: INAD Anaesthetics, time Hospital accounts Costs<br />
USA to recovery Propofol net saving:<br />
Randomisation: Effectiveness data: US $3228<br />
NK INAD<br />
Effectiveness *<br />
Blind: single Outcome data: NA Propofol superior<br />
Power estimate: Cost data: UNACC<br />
NK<br />
Analysis: INAD<br />
Inclusion/exclusion<br />
criteria: NK Sensitivity analysis:<br />
no<br />
Recruitment<br />
rates: NK<br />
Representative<br />
sample: NK<br />
Comparable<br />
groups: NK<br />
Killian et al., 1992, 86<br />
Source: RCT Study design: INAD Anaesthetics and Not known Costs<br />
Canada anti-emetics Propofol TIVA: total cost<br />
Randomisation: Effectiveness data: US $16.41 per patient<br />
yes INAD<br />
Thiopental/isoflurane: total<br />
Blind: no Outcome data:<br />
INAD<br />
cost US $5.45 per patient<br />
Power estimate: Effectiveness<br />
no Cost data: UNACC No difference in terms<br />
of time to open eyes<br />
Inclusion/exclusion Analysis: INAD (immediate recovery),<br />
criteria: 9 Aldrete score, time to<br />
Sensitivity analysis: orientation, PONV.<br />
Recruitment no Propofol TIVA was<br />
rates: NK superior in terms of<br />
intermediate and late<br />
Representative recovery, psychomotor<br />
sample: NK tests and overall recovery<br />
Comparable<br />
groups: yes<br />
Kurpiers et al., Source: RCT Study design: INAD Drug Hospital-specific Costs<br />
1996, 216 USA prices Propofol TIVA: average<br />
Randomisation: Effectiveness data: cost US $31.77 ± 14.44;<br />
yes INAD drug costs US $57.97 ±<br />
20.22<br />
Blind: no Outcome data:<br />
INAD Propofol/desflurane:<br />
Power estimate: average cost US $12.99<br />
no Cost data: UNACC ± 7.61; drug costs<br />
US $34.86 ± 14.13<br />
Inclusion/exclusion Analysis: INAD<br />
criteria: 8 Effectiveness<br />
Sensitivity analysis: PONV: propofol 12% and<br />
Recruitment no desflurane 41% (p < 0.05)<br />
rates: NK<br />
Representative<br />
sample: NK<br />
Comparable<br />
groups: yes<br />
continued<br />
169