Aanesthetic Agents for Day Surgery - NIHR Health Technology ...

a scale effect for scenario A, but not for scenario B,
which was not evident in the piloting work. Many
parents’ responses appear to have been constrained
by the scale, despite pilot work and the
option to provide a value beyond the limits of
the scale. This suggests that the more recent
the experience of anaesthesia, the stronger the
preferences expressed. It also suggests that
the CVs reported here are conservative rather
than extravagant values.
Parents’ preferences for maintenance
of anaesthesia
The parents/guardians of the 260 children in the
CESA RCT were asked for their preference for
scenario C or scenario D (Table 57). The results
Health Technology Assessment 2002; Vol. 6: No. 30
TABLE 56 CVs for induction with intravenous anaesthetic (scenario A) or inhalational anaesthetic (scenario B), by anaesthetic regimen
in the paediatric study (invalid answers excluded)
Anaesthetic regimen No. who chose Mean No. who chose Mean
scenario A (median, SD, range) scenario B (median, SD, range)
CV for scenario A (£) CV for scenario B (£)
Total No. of patients 97 221.4 (200, 177, 0–1000) 131 255.2 (200, 259, 0–2000)
Propofol/halothane 77 227.3 (200, 191,0–1000) 42 207.1 (187.5, 200, 0–1000)
Sevoflurane/sevoflurane 20 198.8 (225, 107, 0–500) 89 277.8 (200, 280, 0–2000)
50
40
30
20
10
0
No. of patients
25 50 75 100 125 150 175 200 225 250 More
© Queen’s Printer and Controller of HMSO 2002. All rights reserved.
CV (£)
FIGURE 21 Distribution of the CVs for induction with intravenous anaesthetic (scenario A) or inhalational anaesthetic (scenario B) in
the paediatric study ( , scenario A; , scenario B)
show that 98% of parents would choose the
scenario where the risk of PONV was reduced.
Those parents who picked scenario C were considered
to have given invalid answers and were
excluded from the analysis.
CVs for maintenance of anaesthesia
Parents were asked to give a value for their
expressed preference. Parents who gave valuations
that were classed as invalid (see appendix 16) were
excluded from the analysis. A minority of parents
who gave responses of ‘more than £250’ but did
not give an actual value were also excluded. A
total of 236 responses were used in this analysis.
Table 58 summarises the CVs given by parents for
maintenance anaesthesia, by randomisation group.
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