effect of infection of the filarial parasite brugia malayi - Pondicherry ...
effect of infection of the filarial parasite brugia malayi - Pondicherry ...
effect of infection of the filarial parasite brugia malayi - Pondicherry ...
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The mf could not be seen in spleen in B.rnalayi infected animals as reported<br />
earlier. This may be because it is an important organ <strong>of</strong> immune system <strong>of</strong> <strong>the</strong> body. The<br />
fact is substantiated by mild! lymphoid hyperplacia and presence <strong>of</strong> giant cells observed<br />
in spleen <strong>of</strong> infected animals. This is in agreement with earlier reports by Duke (1960)<br />
and Mak et al. (1984), where spleen was unaffected by 5, <strong>malayi</strong> <strong>infection</strong>. Thus <strong>the</strong><br />
morphological changes seen in <strong>the</strong> spleen would be dependent on <strong>the</strong> state <strong>of</strong> <strong>the</strong> host's<br />
patho-immunological responses. To find <strong>the</strong> specific cells <strong>of</strong> <strong>the</strong> immune system<br />
responsible for killing <strong>of</strong> mf and <strong>the</strong> irreversible testicular damage may be ano<strong>the</strong>r<br />
interesting field for fur<strong>the</strong>r investigation.