effect of infection of the filarial parasite brugia malayi - Pondicherry ...

More documents

Recommendations

Info

Marshall, G.R., Wickings, E.J. and Nieschlag, E. (1984). Testosterone can initiate spermatogenesis in an immature non-human primate, Macaca fascicularis. Endocrinol. 114: 2228. Mathews, S.T. and Selvam, ~.'(1991a). Effect of radical treatment on erythrocytic lipid peroxidation in Plasmodium viva infected malaria patients. Biochem. Int. 25 (2): 211. Mathews, S.T. and Selvam, R. (1993). Changes in glutathione metabolic enzymes in erythrocytes of Plasmodium viva infected patients. CIin Chim. Acla. 219: 159. Mathews, S.T., Kumaresan, P.R. and Selvam, R. (1991). Glucose-bghosphate dehydrogenase deficiency and malaria. A study on North Madras population. J. Cornm. Dis. 23 (3): 178. McCall, J.W., Malone, J.B., Hyang, E. and Thompson, P.E. (1973). Mongolian jirds (Meriones unguiculatus) infected with B. pahangi by the intraperitoneal route: A rich source of developing larvae, adult filariae, and microfilaria. Vet. Parasirol. 59 (3): 436. McCord, J.M. and Fridovich, 1. (1969). Superoxide dismutase. An enzymatic function for erythrocuprein (Hernocuprein). 244 (22): 6049. McCormick, J.R., Harkin, M.M., Johnson, K.J. and Ward, P.A. (1 98 1). Suppression by superoxide dismutase of immune complex induced pulmonary alveolitis and dermal inflammation. Amer. J. Pathol. 102: 55. McIlwain, H. (1969). In: Basic mechanisms of epilepsies, Jasper, H.H., Ward, .A.A. and Pope, A, Eds., Little Brown, Boston, pp 83. Miale, J.B. (1972). Appendix methods. In: Laboratory medicine haematology. 4th ed., Mosby, C.V.co., St. Louis, pp 904, 1 198, 1200. Mitchell, C.D., Mitchell, W.B. and Hanahan, D.J. (1965). Enzyme and haemoglobin retention in human erythrocyte stroma. Biochem. Biophys. Acta. 104: 348. Morikov, K.N., Herrera, M., Pascual, C. and Gonzalez, R. (1991). The antioxidative activity of drugs in the liver microsomal system of rats. Biol. yauki. 12: 19. Moron, MS., Depierre, J.W. and Mannerviek, B. (1979). Levels of glutathione and glutathione-S-transferase activities in rat lung and liver. Biochem. Biophys. Acta. 582: 67. Murthy, P.K., Murthy, P.S., Tyagi, K. and Chatterjee, R.K. (1997). Fate of infective larvae of B. malayi in the peritoneal cavity of M. natalensis and Meriones unguiculatus. Folia parasit. 44 (4): 302.
Murray, H.W. (1981). Susceptibility of Leismania to oxygen intermediates and killing by normal macrophages. J. Exp. Med. 153: 1302. Nair, C.R., Gupta, P.H., Chauhan, D.P., Bhatia, A. and Vinayak, V.K. (1981). A study on the mechanism of impaired oxidative drug metabolism in experimental malaria in mice. Ind J. Mal. Res. 74: 829. Nair, C.R., Gupta, P.H., Chauhan, D.P. and Vinayak. V.K. (1984). Peroxidative changes in erythrocytic enzymes in Plasmodium berghei induced malaria in mice. lnd. J Med. Res. 80: 627. Nathan, C.F. and Root, R.K. (1977). Hydrogen peroxide release from mouse peritoneal macrophages. J. Exp. Med. 146: 1648. Nicholls. 1. (1965). Activity of catalase in red cell. Biochem. Biophys. Acta. 99: 286 Niki, E., Saito, T., Kawakami, A. and Kamiya, Y. (1984). Inhibition of oxidation of methyl lineoleate in solution by vitamin E and C. J. Biol. Chem. 259: 477. Nishikimi, M. (1975). Oxidation of ascorbic acid with superoxide ion generated by the xanthine oxidase system. Biochem. Biophys. Res. Comm. 63: 463. Ogilvie, B.M., Hesketh, P.M. and Rose, M.E. (1978). Nippostrongylus brasiliensis: peripheral blood leucocyte response of rats with special reference to basophils. Expt. Parasit. 46: 20. Ohinishi, T., Suzuki, Y. and Ozawa, K. (1982). A comparative study of plasma membrane magnesium-ion ATPase activities in normal, regenerating and malignant cells. Biochem. Biophys. Acta. 684: 67. Omaye, S.T., Turnbull, J.D. and Sauberlich, H.E. (1979). Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. Method. Enzymol. 62: 1. Orlowski, M. and Meister, A. (1965). Isolation of y-glutamyl transpeptidase from hog kidney. J. Biol. Chem. 240: 338. Ottesen, E.A. and Nutman, T.B. (1992). Tropical pulmonary eosinophilia. Ann. Rev. Med. 43: 418. Ottolengi, A. (1959), Interaction of ascorbic acid and mitochondria1 lipids. Arch. Biochem. Biophys. 79: 355. Paily, K.P., Gomathi, K., Hoti, S.L., Balaraman, K. and Dhanda, V. (1995). A report on the demonstration of microfilbriae of Brugia malayi ~n,the brain of an experimental animal host, Mastomys natalensis. lnt. J. Parasit. 25 (9): 1123.
Page 1 and 2:
EFFECT OF INFECTION OF THE FILARIAL
Page 4 and 5:
I wish to express my deep sense of
Page 6:
1. INTRODUCTlON 2. REVIEW OF LlTERA
Page 9 and 10:
As stated earlier, the host immune
Page 11 and 12:
13 Testicular changes Testosterone
Page 14 and 15:
2. REVIEW OF LITERATURE Filariasis
Page 16 and 17:
2.2 Clinical signs Inflammalation o
Page 18 and 19:
the tegument by the release of thei
Page 20 and 21:
the compound kills the filarial wor
Page 22:
3. MATERIALS AND METHODS COLONY MAI
Page 25 and 26:
Ragenb 1. Tris-HCI buffer . : 0.1 M
Page 27 and 28:
3. Reduced glutathione : 30 mM To I
Page 29 and 30:
4.1.1.6 Glucose-6-phosphate dehydro
Page 31 and 32:
absorbance of the clear supernatant
Page 33 and 34:
-eats I. Lowry's reagent :Solution
Page 35 and 36:
4.1.2.1 Changes in antioxidant enzy
Page 37 and 38:
Fig.3: Effect of B.malayi on SOD in
Page 39 and 40:
Fig.9: Effect of B.rnalayi on GST i
Page 41 and 42:
Fig.12: Effect of 6.rnalayi on GPx
Page 43 and 44:
Fig. 18: Effect of B.malayi on G6PD
Page 45 and 46:
12- 3 m- 15- lor, Fig.21: Effect of
Page 47 and 48:
Fig.27: Effect of B.malayi on Ascor
Page 49 and 50:
4.1.2.3 Change in the antioxidant e
Page 51 and 52:
Fig.35: Effect of B.malayi on CAT i
Page 53 and 54:
m 20 0) - 15 9 g 10 il! 5 0 Fig.39:
Page 55 and 56:
30 25 8 - a 20 2 15 C I 10 I 5 0 35
Page 57 and 58:
Fig.45: Effect of B.maiayi on GSH i
Page 59 and 60:
Fig.49: Effect of B.malayi on Vit-C
Page 61 and 62:
4.1.3 DISCUSSION 4.1 3.1.1 Toxic ox
Page 63 and 64:
1973). The two major systems of LPO
Page 65 and 66:
1981), and their increase in human
Page 67 and 68:
1 0 Fig.58:Relationship between cha
Page 69 and 70:
1 - 0- ' 1 5 - 6 - 7 - Fig.63:Relat
Page 71 and 72:
Catalase had been reported to be re
Page 73 and 74:
- Fig.68:Relationship between chang
Page 75 and 76:
esults in its reduced activity (Con
Page 77 and 78:
g 20- :I-. F1g.70:Relationship betw
Page 79 and 80:
12, - I 0 U) Q 4 2 0 - + - Fig.75:R
Page 81 and 82:
$ Fig.80:Relationship between chang
Page 83 and 84:
Fig.85:Relationship between change
Page 85 and 86:
V) (3 :; - Fig.9O:Relationship betw
Page 87 and 88:
A reduction in the total thiol cont
Page 89 and 90:
2 5- Fig.98:Relationship between ch
Page 91 and 92:
Fig. 103:Relationship between chang
Page 93 and 94:
4.2.1.1 N ay ATPase Reagents Nay AT
Page 95 and 96:
Reagents 1. Acetylcholine bromide :
Page 97 and 98:
To 1.5 ml of carbonate buffer, 1.5
Page 99 and 100:
4.2.1.10 Differential leucocyte cou
Page 101 and 102: increase in the control animals (Fi
Page 103 and 104: - Fig.110: Effect of 6. malayi on H
Page 105 and 106: efflux and thereby alter the membra
Page 107 and 108: with i n d lymphocytes and decrease
Page 109 and 110: Tubes were labeled for calibrators,
Page 111 and 112: Fig.114: Effect of B, malayi on GTP
Page 113 and 114: 433 DISCUSSION Testosterone is a se
Page 115 and 116: CHAPTER 4.4 HISTOPATHOLOGICAL CHANG
Page 117 and 118: Platc 2 Plate 3 Plate 4 Plate 5 Pla
Page 119 and 120: Platc X Plate 9 Plate 10 Plate 11 P
Page 121 and 122: Plate w: Section of Testes of norma
Page 123 and 124: 4.4.2.1.5 Brain The control animals
Page 126 and 127: Plate ICt Section of Kidney of infe
Page 128 and 129: 4.4.2.2 Histopathological changes i
Page 130 and 131: Plate 32
Page 132: The mf could not be seen in spleen
Page 135 and 136: ain, it decreased from 0 day itself
Page 137: inflammatory nature indicative of c
Page 141 and 142: BIBLIOGRAPHY Ackerman, S.J., Gleich
Page 143 and 144: Case, T., Leis, B., Witte, M., Way,
Page 145 and 146: Drabkin, D.L.R. and Austin, J.H. (1
Page 147 and 148: Fukuota, M., Zhou, Y. and Tanaka.(l
Page 149 and 150: Jacob, H.S. and Lux, S.E. (1968). D
Page 151: Linda, I. and Mayeda, B. (1974). Th
Page 155 and 156: Santiago- Stevenson, D., Oliver-Gon
Page 157 and 158: Tate, S.S., Thomson, G.A. and Meist
Page 159 and 160: Zaini, M., Ramachandran, C.P. and E
show all

effect of infection of the filarial parasite brugia malayi - Pondicherry ...

Create successful ePaper yourself

Delete template?

Save as template?