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CMS Manual System - Louisiana Department of Health and Hospitals

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o Support decisions about modifying, discontinuing, or continuing any<br />

interventions.<br />

―Neuroleptic Malignant Syndrome‖ (NMS) is a syndrome related to the use <strong>of</strong><br />

medications, mainly antipsychotics, that typically presents with a sudden onset <strong>of</strong><br />

diffuse muscle rigidity, high fever, labile blood pressure, tremor, <strong>and</strong> notable<br />

cognitive dysfunction. It is potentially fatal if not treated immediately, including<br />

stopping the <strong>of</strong>fending medications.<br />

―Non-pharmacological interventions‖ refers to approaches to care that do not<br />

involve medications, generally directed towards stabilizing or improving a<br />

resident‘s mental, physical or psychosocial well-being.<br />

―Psychopharmacological medication‖ is any medication used for managing<br />

behavior, stabilizing mood, or treating psychiatric disorders.<br />

―Serotonin Syndrome‖ is a potentially serious clinical condition resulting from<br />

overstimulation <strong>of</strong> serotonin receptors. It is commonly related to the use <strong>of</strong><br />

multiple serotonin-stimulating medications (e.g., SSRIs, SNRIs, triptans, certain<br />

antibiotics). Symptoms may include restlessness, hallucinations, confusion, loss<br />

<strong>of</strong> coordination, fast heart beat, rapid changes in blood pressure, increased body<br />

temperature, overactive reflexes, nausea, vomiting <strong>and</strong> diarrhea.<br />

―Tardive dyskinesia‖ refers to abnormal, recurrent, involuntary movements that<br />

may be irreversible <strong>and</strong> typically present as lateral movements <strong>of</strong> the tongue or<br />

jaw, tongue thrusting, chewing, frequent blinking, brow arching, grimacing, <strong>and</strong><br />

lip smacking, although the trunk or other parts <strong>of</strong> the body may also be affected.<br />

OVERVIEW<br />

Medications are an integral part <strong>of</strong> the care provided to residents <strong>of</strong> nursing facilities.<br />

They are administered to try to achieve various outcomes, such as curing an illness,<br />

diagnosing a disease or condition, arresting or slowing a disease process, reducing or<br />

eliminating symptoms, or preventing a disease or symptom.<br />

A study <strong>of</strong> 33,301 nursing facility residents found that an average <strong>of</strong> 6.7 medications<br />

were ordered per resident, with 27 percent <strong>of</strong> residents taking nine or more medications. 52<br />

Analysis <strong>of</strong> antipsychotic use by 693,000 Medicare nursing home residents revealed that<br />

28.5 percent <strong>of</strong> the doses received were excessive <strong>and</strong> 32.2 percent lacked appropriate<br />

indications for use. 53<br />

Proper medication selection <strong>and</strong> prescribing (including dose, duration, <strong>and</strong> type <strong>of</strong><br />

medication(s)) may help stabilize or improve a resident‘s outcome, quality <strong>of</strong> life <strong>and</strong><br />

functional capacity. Any medication or combination <strong>of</strong> medications—or the use <strong>of</strong> a<br />

medication without adequate indications, in excessive dose, for an excessive duration, or<br />

without adequate monitoring—may increase the risk <strong>of</strong> a broad range <strong>of</strong> adverse

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