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CMS Manual System - Louisiana Department of Health and Hospitals

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iperiden trihexyphenidyl olanzapine thioridazine<br />

MUSCLE RELAXANTS<br />

cyclobenzaprine dantrolene<br />

orphenadrine<br />

ANTIVERTIGO MEDICATIONS<br />

meclizine scopolamine<br />

URINARY INCONTINENCE<br />

oxybutynin probantheline<br />

solifenacin tolterodine<br />

trospium<br />

PHENOTHIAZINE ANTIEMETICS<br />

prochlorperazine promethazine<br />

Potential Adverse Consequences <strong>of</strong> Medications with Anticholinergic Properties<br />

Blood pressure, increased Breathing difficulty, changes<br />

Clumsiness or unsteadiness Convulsions<br />

Digestive system changes, e.g.,<br />

Mental status/behavior changes, e.g.,<br />

Bloating<br />

Distress, excitement, nervousness<br />

Bowel motility, decreased<br />

Attention, impaired<br />

Constipation<br />

Cognitive decline<br />

Ileus, paralytic/adynamic<br />

Confusion/disorientation<br />

Nausea or vomiting<br />

Hallucinations<br />

Swallowing difficulty with dry mouth Memory loss<br />

Restlessness or irritability<br />

Delirium Dizziness<br />

Drowsiness Fever<br />

Headache Heart rate, increased<br />

Lethargy, fatigue Mucous membrane dryness: mouth, nose<br />

Muscle weakness, severe Speech, slurring<br />

Skin, changes<br />

Vision impairment, changes in acuity<br />

Dryness Sweating, decreased<br />

Blurring Glaucoma, worsening<br />

Flushing Warmth, excessive<br />

Urinary retention or difficulty<br />

Eye pain Light sensitivity<br />

ENDNOTES<br />

61 Tune, L. Carr, S., Hoag, E. & Cooper, T. (1992). Anticholinergic effects <strong>of</strong> drugs commonly<br />

prescribed for the elderly: Potential means for assessing risk <strong>of</strong> delirium. American<br />

Journal <strong>of</strong> Psychiatry, 149, pp. 1393-1394.<br />

62 Tune, L.E. (2000). Serum anticholinergic activity levels <strong>and</strong> delirium in the elderly. Seminars<br />

in Clinical Neuropsychiatry, 5, pp. 149-153.

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