university of kwazulu-natal faculty of science and agriculture school ...

Position
Compound IV
(600MHz)
4.1 4.2 4.3
b
da Graca
Rocha et al.,
2007
(200MHz)
a Fang et al.,
1991
(75MHz)
a Lontsi et al.,
1992
(75MHz)
a Fang et al.,
1991
(75MHz)
a Lontsi et al., 1998
(75MHz)
23 27.89 28.8
28.5
28.5
28.5
28.55
24 21.09 17.1 16.7 21.8 21.8 16.72
25 15.51 16.6 16.4 16.2 16.1 16.36
26 16.15 23.3 16.7 16.6 17.9 16.42
27 23.55 24.0 224.3 24.7 24.6 24.37
28 180.88 179.0 178.2 178.2 178.4 178.26
29 25.68 26.4 28.0 27.4 27.2 27.18
30 15.25 16.5 15.9 16.1 16.5 15.97
COOCH3 -- -- 51.4 51.6 66.2 51.46
a CDCl3
b DMSO
Table 24: Comparison of 1 H NMR data of compound IV (600MHz, CD3OD) with three
reference compounds
Position Compound IV
1
2
3
1.28
1.56
3.93, dt
(J = 3.72, 3.18 Hz)
3.33, d
(J = 2.28 Hz)
4.1 4.2 4.3
b # da Graca Rocha et al.,
2007
(200MHz)
4.10, m
3.91, s
a Lontsi et al., 1992
(300MHz)
1.21, m
1.62, m
3.97, ddd
(J = 11.8, 4.4, 2.8 Hz)
3.40, d
(J = 2.8 Hz)
a Lontsi et al., 1998
(300MHz)
0.92, m
1.96, m
3.36, ddd
(J = 14.7, 9.5, 4.7 Hz)
2.98, d
(J = 9.5 Hz)
5 1.26 0.81, m
6
1.39
1.45
1.32, m
1.52, m
7
1.31
1.58
1.26, m
1.50, m
9 1.85 1.70, m 1.65, m
11 2.00 1.96, m 1.98, m
12
15
16
5.29, t
(J = 3.72 Hz)
*5.19, s
5.33, dd
(J = 3.6, 3.5 Hz)
5.33, dd
(J = 3.6, 3.6 Hz)
1.01 1.00, m
1.79 1.60, m
1.51 1.56, m
2.57
2.49, ddd
(J = 13.7, 11.5, 4.7 Hz)
2.49, ddd
(J = 14.5, 12.6, 4.8 Hz)
18 2.49 2.57, s 2.57, s
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