university of kwazulu-natal faculty of science and agriculture school ...

Position Compound IV
4.1 4.2 4.3
b # da Graca Rocha et al.,
2007
(200MHz)
a Lontsi et al., 1992
(300MHz)
a Lontsi et al., 1998
(300MHz)
20 1.35
1.38, m
21
1.23
1.73
1.25, m
1.66, m
22
1.61
1.71
1.52, m
1.72, m
23 0.98 0.99, s 1.01, s
24 0.86 0.84, s 0.80, s
25 0.98 0.93, s 0.95, s
26 0.78 0.64, s 0.65, s
27 1.35 1.23, s 1.23, s
29 1.19 1.18, s 1.19, s
30
0.92, d
0.92, d
0.92, d
28-
OCH3
(J = 7.8 Hz)
(J = 6.6 Hz)
3.57, s
(J = 6.7 Hz)
3.58, s
NB 1 H NMR data for compounds 4.2 and 4.3 were not documented by Fang et al. (1991)
* Reported as resonance for H-5 by da Graca Rocha et al. (2007) but suspect that this resonance belongs to
H-12
# coupling constants not documented
a CDCl3
b DMSO
3.4.4 Structure elucidation of Compounds V and VI
HO
3
19
5
10
6
7
21
18
14
20
22
29
16
23
28
27
25
26
HO
3
25 26
24 23
(V) (VI)
Compound V is a white compound soluble in both dichloromethane and methanol having
a molecular formula of C29H42O. It has a melting point of 168°C and an optical rotation
10
30
20
29
27
18
19
17
22
28
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