Pesticide residues in food — 2006: Toxicological ... - ipcs inchem

43
Medical data
No significant adverse health effects reported
Summary
Value Study Safety factor
ADI
0–0.01 mg/kg bw
Dog, one-year study of
toxicity
100
ARfD Unnecessary — —
References
Andre, J.C. & McClanahan, R.H. (1997) Pilot study of the routes of elimination of radiolabel following oral
administration of 14 C-D2341 to Sprague-Dawley rats. Unpublished report (study No. 95-0045; EPA FIFRA
guideline 85-1) dated February 21, from Ricerca Inc., Painesville, Ohio, USA. Submitted to WHO by
Crompton Corporation, Middlebury, Connecticut, USA.
Banijamali, A.R. (2001) Metabolism of 14 C-bifenazate following oral doses of 12 C-bifenazate to Sprague Dawley
rats. Unpublished report (Uniroyal study No. 2000-102; Ricerca study No 12434; OECD guideline 417)
dated February 28, from Uniroyal Chemical Company, Middlebury, Connecticut, USA and Ricerca LLC,
Painesville, Ohio, USA. Submitted to WHO by Crompton Corporation, Middlebury, Connecticut, USA.
Denny, K.H. (1996) Range-finding developmental toxicity study in New Zealand White rabbits with D2341.
Unpublished report (study No. 399-182) dated May 7, from MPI Research, Mattawan, Michigan, USA.
Submitted to WHO by Crompton Corporation, Middlebury, Connecticut, USA.
Goldenthal, E.I. (1997) 90-Day dietary toxicity study in dogs. Unpublished report (study No. 399-191; EPA
FIFRA guideline 82-1) dated August 20, from MPI Research, Mattawan, Michigan, USA. Submitted to
WHO by Crompton Corporation, Middlebury, Connecticut, USA.
Goldenthal, E.I. (1998) 21-Day dermal toxicity study in rats. Unpublished report (study No. 399-197; EPA
FIFRA guideline 82-2, OECD guideline 410 and MAFF guidelines 59 NohSan No. 4200) dated October
20, from MPI Research, Mattawan, Michigan, USA. Submitted to WHO by Crompton Corporation,
Middlebury, Connecticut, USA.
Goldenthal, E.I. (1999) One Year dietary toxicity study in dogs. Unpublished report (study No. 399-192; EPA
FIFRA guideline 83-1 and MAFF guidelines 59 NohSan No. 4200) dated January 20, from MPI Research,
Mattawan, Michigan, USA. Submitted to WHO by Crompton Corporation, Middlebury, Connecticut, USA.
Gudi, R. (1996) Micronucleus cytogenetic assay in mice with D2341. Unpublished report (study No. G96AJ85.122;
EPA FIFRA guideline 84-2) dated October 4, from Microbiological Associates Inc., Rockville, Maryland,
USA. Submitted to WHO by Crompton Corporation, Middlebury, Connecticut, USA.
Gudi, R. & Schadly, E.H. (1996) In vitro mammalian cytogenetic test with an independent repeat assay.
Unpublished report (study No. G96AJ85.335) dated, December 3, from Microbiological Associates Inc.,
Rockville, Maryland, USA. Submitted to WHO by Crompton Corporation, Middlebury, Connecticut, USA.
Hoffman, G. (1996a) An acute (4-hour) inhalation toxicity study of D2341 technical in the rat via noseonly
exposure. Unpublished report (study No. 95-5239; EPA FIFRA guideline 81-3) dated August 8,
from Huntingdon Life Sciences, East Millstone, New Jersey, USA. Submitted to WHO by Crompton
Corporation, Middlebury, Connecticut, USA.
BIFENAZATE X-X JMPR 2006