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Pesticide residues in food — 2006: Toxicological ... - ipcs inchem

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54<br />

Figure 2. Transfer of radioactivity across rat and human epidermal membranes after a s<strong>in</strong>gle<br />

a pplication of [ 14 C]boscalid at a nom<strong>in</strong>al dose of 10 μg/cm 2 (1 mg/ml)<br />

5.0<br />

4.5<br />

μg equivalents boscalid/cm 2<br />

4.0<br />

3.5<br />

3.0<br />

2.5<br />

2.0<br />

1.5<br />

1.0<br />

0.5<br />

Rat<br />

Human<br />

0.0<br />

0 3 6 9 12 15 18 21 24<br />

Exposure time (h)<br />

From Thornley & Bryson (2001)<br />

Figure 3. Transfer of radioactivity through rat and human epidermal membranes after a s<strong>in</strong>gle<br />

application of [ 14 C]boscalid at a nom<strong>in</strong>al dose of 100 μg/cm 2 (10 mg/ml)<br />

5.0<br />

2<br />

μg equivalents boscalid absorbed/cm<br />

4.5<br />

4.0<br />

3.5<br />

3.0<br />

2.5<br />

2.0<br />

1.5<br />

1.0<br />

0.5<br />

Rat Human<br />

0.0<br />

9<br />

0 3 6 12 15 18 21 24<br />

Exposure time (h)<br />

From Thornley & Bryson (2001)<br />

BOSCALID X-X JMPR <strong>2006</strong>

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