Vol 21 No. 1
Vol 21 No. 1
Vol 21 No. 1
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J Bagh College Dentistry <strong>Vol</strong>. <strong>21</strong>(1), 2009 The role of lipid peroxidation …<br />
The role of lipid peroxidation in the inducation and<br />
progression of chronic periodontitis.<br />
Taghreed F. Zaidan B.D.S.,M.Sc., Ph.D. (1)<br />
ABSTRACT<br />
Backgrounds: Free-radical-induced lipid peroxidation has been implicated in the pathogenesis of several<br />
pathological disorders. This study was aimed to assess the degree of oxidative stress in patients with chronic<br />
periodontitis by estimation of plasma and saliva lipid peroxidation product malondialdehyde (MDA), and the<br />
antioxidants erythrocyte glutathione (GSH), plasma and saliva thiol.<br />
Patients and methods: Fifty patients with chronic periodontitis with mean age of 32.6 ± 10.3 years and fifty healthy<br />
control subjects with normal gingival age study, 5 mls of blood and 3 mls of unstimulated saliva was collected from<br />
each subjects for estimation of plasma and saliva MDA, thiol and erythrocyte glutathione spectrophotometricaly.<br />
Results: The results showed that significantly increased p