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P OSTER A BSTRACTS contribution by heightened immune activation to age-associated accelerated HIV disease progression has not been delineated. Methods: Prospective, age-differentiated, multicenter cohort study of older (≥45 years) and younger (18-30 years) subjects who received 192 weeks of a uniform ART regimen. Age-group differences in the time course of a diverse array of immunologic indices were assessed with adjustment for other correlates of T cell restoration in mixed-effects models. Results: 90 subjects enrolled in this cohort, including 45 younger (median age 26, range 18-30 yrs) and 45 older (median age 50, range 45-79 yrs) subjects. The increases of naive, memory and total CD4 cells, and naïve CD8 cells per week with ART did not differ significantly between the age-groups, but older subjects maintained significantly fewer circulating naive ( P
P OSTER A BSTRACTS ing decisions when patients develop dementia. The purpose of this study was to describe the perspectives of family caregivers toward forgoing or continuing cancer screening. We audio-taped and transcribed focus group sessions with a convenience sample of caregivers of patients with dementia attending 4 local Alzheimer’s Association support groups. Session topics included recent experiences with screening decisions and preferences for patient-clinician communication. The interviews were coded independently by all investigators to identify key themes using methods of grounded theory. We conducted 4 focus group sessions with 32 caregivers of patients with dementia. Mean age was 65.5 (range 49-85), 25 were women, 7 were African American, 24 white, and 1 African American/Indian. Caregivers were 14 daughters, 13 were spouse, and 5 other. The most important factor in making decisions about screening tests preserving the patient’s Quality of Life. One said, “I was concerned about her quality of life and making sure that she was very, very comfortable, and I think that means more than putting people through a lot of unnecessary, uncomfortable…procedures.” The second theme involved the Increasing Burdens and Decreasing Benefits of continued screening as dementia worsened. Specifically, the inability to understand procedures and patient agitation increased the test burdens. Caregivers noted their own Pivotal Role in Decision Making, often stepping in to stop invasive tests and deciding when to take over decision making from the patient. Caregivers noted variable levels of Physician Knowledge/Expertise, with some having limited knowledge of the course or challenges of dementia. Caregivers of patients with dementia consider cancer screening tests in light of their impact on quality of life. Given their perceptions of the changing balance of burdens and benefits as dementia worsens, many caregivers choose to forgo screening. The perspective of caregivers contrasts with prior research on patient perspectives, which finds that many patients plan to continue screening for themselves despite possible future declines in health. B145 Older Adult Opinions of “Advanced Driving Directives” M. E. Betz, 1 S. Lowenstein, 1 R. Schwartz. 2 1. Emergency Medicine, University of Colorado School of Medicine, Aurora, CO; 2. Division of Geriatrics, University of Colorado School of Medicine, Aurora, CO. Supported By: Emergency Medicine Foundation and John A Hartford University of Colorado Denver Center of Excellence. BACKGROUND: Discussions and decisions about driving retirement are difficult. “Advanced driving directives” [ADDs], similar to advanced directives for end-of-life care, would allow drivers to designate a person to help make decisions about driving cessation when their driving skills decline. It is not known if older drivers support the idea of ADDs; we sought to describe older adults’ experiences and opinions about driving discussions and ADDs”. METHODS: A convenience sample of English-speaking adults (55+ years) at two independent living facilities and two community centers were invited to complete an anonymous survey. RESULTS: Of the 168 participants, 133 (80%) were female and the median age was 76.5 (range: 56-93) years. Most reported driving a motor vehicle at least occasionally (96%; 95%CI:92-98) and only 29% (95CI:22-37) found driving somewhat or very stressful. Seven percent (95CI:4-12) reported a crash in the past year. Most participants (73%; 95CI:66-80) supported mandatory age-based driver testing; of these, half (50%; 95CI:40-59) though testing should begin at age 80 or higher. More thought that the driver (71%; 95CI65-78), family (61%; 95CI:53-68) or physician (59%; 95CI:51-66) should determine license revocation for an unsafe driver rather than the department of motor vehicles (32%; 95CI:25-39). A minority had spoken with someone about driving safety (5%; 95CI:2-10) or wishes when driving skills decline (21%; 95CI:15-28); of these, 83% (95CI:67-94) had spoken with a family member but only 17% (95CI:6-33) with a healthcare provider. However, older adults were open to discussions (table) and 54% (95CI:46-62) said they would complete an ADD if recommended. Of these, 79% (95CI:69-87) said it was likely or very likely they would follow the ADD in the future. CONCLUSION: Older drivers are open to driving discussions with physicians, supporting the important physician role in counseling and coordinating conversations about driving. Advanced planning with ADDs may facilitate future decisions about driving retirement. B146 Walking Ability is Associated with Pain, Depression, and Overweight among Community Dwelling Older Adults. N. Satchidanand , 1 C. Fox, 1 K. Brunton, 2 G. S. Cherr . 2 1. Family Medicine, State University of New York at Buffalo, Buffalo, NY; 2. Surgery, State University of New York at Buffalo, Buffalo, NY. Supported By: American Geriatrics Society: Dennis W. Jahnigen Career Development Scholars Awards Program. BACKGROUND: Maintenance of mobility is an important goal for the elderly. Impaired physical function limits the ability of older adults to live independently and is strongly associated with declining health. The association between physical comorbidities and disability is well studied. However, less is known about the influence of modifiable factors on physical function. The study purpose was to examine the influence that select treatable factors have on walking ability among older adults. METHODS: A total of 200 subjects, age ≥65 were included (62.5% female). Depressive symptoms, psycho-social stress and chronic pain were assessed using literature validated questionnaires. Body mass index (BMI) was calculated. Physical function was assessed using the Six Minute Walk Test. Pre-existing medical conditions which may impact walking ability (i.e. PAD, COPD, CHF) were also assessed. Path analysis was performed to characterize the contribution of each predictor variable (depression, stress, chronic pain, BMI) on distance walked and to derive path coefficients, R 2 -values and probability values. RESULTS: The predictor variables demonstrated low to moderate correlations with one another, (0.27 to 0.54). Depressive symptoms, pain and BMI (but not psychosocial stress) were significant predictors of distance walked.The overall causal model accounted for about 30% of the variance in distance walked among all patients. After adjusting for pre-existing medical conditions, the proposed model still accounted for about 30% of the variance in distance walked.The strongest association with distance walked was with chronic pain for both the overall model (β = -.296, p < .01) and adjusted model (β = -.250, p < .01). CONCLUSIONS: Among community dwelling older adults, three treatable factors were significantly associated with impaired walking ability. These associations remained after adjusting for medical conditions that are also associated with impaired physical function. Further research is needed to determine the most efficacious interventions to treat depression, ameliorate chronic pain, and prevent weight gain in aging in order to preserve physical function and quality of life. B147 “SERIOUSLY ILL OCTOGENARIANS & NONAGENARIANS”– ROLE OF PALLIATIVE CARE CONSULTS IN INITIATING “DO NOT ESCALATE CARE” PATHWAY AND DISCHARGE TO HOSPICE IN SERIOUSLY ILL OLDEST OLD PATIENTS ADMITTED TO A TERTIARY ACADEMIC MEDICAL CENTER. F. Kawai, V. Periyakoil. Stanford University School of Medicine, Stanford, CA. Supported By: Stanford University School of Medicine Background: AGS 2012 ANNUAL MEETING S123
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Dear Annual Meeting Attendee: The A
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P APER A BSTRACTS the National Deat
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P APER A BSTRACTS two counts were u
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P APER A BSTRACTS management in col
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P APER A BSTRACTS creating a barrie
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P APER A BSTRACTS Conclusion: This
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P APER A BSTRACTS each definition
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P OSTER A BSTRACTS been ruled out.
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P OSTER A BSTRACTS Discussion: Angi
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P OSTER A BSTRACTS calcitriol via 1
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P OSTER A BSTRACTS ii J Clin Micrbi
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P OSTER A BSTRACTS is on the rise.
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P OSTER A BSTRACTS edema (60%), and
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P OSTER A BSTRACTS categories based
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P OSTER A BSTRACTS Methods: A longi
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P OSTER A BSTRACTS Design. CaMos is
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P OSTER A BSTRACTS incidents (64%)
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P OSTER A BSTRACTS TNF-R1 levels we
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P OSTER A BSTRACTS curriculum betwe
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P OSTER A BSTRACTS A75 Geriatrics a
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P OSTER A BSTRACTS Design: Based on
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P OSTER A BSTRACTS medicine fellows
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P OSTER A BSTRACTS While we were no
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P OSTER A BSTRACTS This study’s p
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P OSTER A BSTRACTS and its sum of b
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P OSTER A BSTRACTS NTM infection wa
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P OSTER A BSTRACTS death because
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P OSTER A BSTRACTS A158 Curved Path
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P OSTER A BSTRACTS C118 Patient and
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P OSTER A BSTRACTS C141 Contributio
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P OSTER A BSTRACTS nal process can
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P OSTER A BSTRACTS Case: A 78 year-
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P OSTER A BSTRACTS then awoke spont
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P OSTER A BSTRACTS D32 Comparison o
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P OSTER A BSTRACTS rate was 21.9% f
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P OSTER A BSTRACTS and geriatrics c
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P OSTER A BSTRACTS survey using the
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P OSTER A BSTRACTS D102 Clinician
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P OSTER A BSTRACTS D114 Fall Reduct
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P OSTER A BSTRACTS D120 Geropsychia
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P OSTER A BSTRACTS In addition to 7
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P OSTER A BSTRACTS D144 The Use of
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A UTHOR I NDEX Azhar, G . . . . . .
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A UTHOR I NDEX Ceimo, J . . . . . .
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A UTHOR I NDEX Dunn, C M . . . . .
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A UTHOR I NDEX Griebling, T L . . .
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A UTHOR I NDEX Johnson, K . . . . .
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A UTHOR I NDEX Levine, M . . . . .
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A UTHOR I NDEX Mulsant, B . . . . .
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A UTHOR I NDEX Pschirer, J P . . .
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A UTHOR I NDEX Sheppard, K D . . .
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A UTHOR I NDEX Ukritchon, S . . . .
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K EYWORD 25-hydroxyvitamin D . . .
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K EYWORD I NDEX Colorectal cancer s
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K EYWORD I NDEX Geriatric curriculu
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K EYWORD I NDEX Medication discrepa
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K EYWORD I NDEX Race . . . . . . .
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