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Here - American Geriatrics Society

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P OSTER<br />

A BSTRACTS<br />

incidents (64%) regardless of age or the presence of alcohol.The odds<br />

of an injury being due to a fall or motor vehicle accident in BAL+ patients<br />

compared to BAL- patients can be seen the table below.<br />

When controlling for the selected demographic factors and the<br />

presence of alcohol, the odds of an injury being the result of a fall increased<br />

significantly as patient age increased. Conversely, the odds of<br />

an injury being from a motor vehicle accident decreased significantly<br />

as the patient age increased.<br />

Conclusions: Age as well as alcohol does influence the odds of<br />

an injury being due to a fall or a motor vehicle accident in older<br />

adults. Our findings suggest that alcohol related injury prevention<br />

programs should be tailored to the age group targeted.<br />

Unadjusted odds of injury being due to falls or motor vehicle accident<br />

by age group<br />

A58<br />

Long term treatment with metformin in patients with type 2 diabetes<br />

and risk of vitamin B-12 deficiency.<br />

V. Nurpeisov. Emory, Dunwoody, GA.<br />

Background: Identification of risk factors for metformin-related<br />

vitamin B12 deficiency has major potential implications regarding the<br />

management of DM.<br />

Methods: A case-control study was conducted from a database<br />

in which the source population consisted of subjects who had levels of<br />

both serum vitamin B12 and hemoglobin A1C checked in a laboratory.<br />

63 cases of diabetes mellitus (HbA1C>7) and vitamin B12 deficiency<br />

secondary to metformin treatment were identified. 73 controls<br />

which were identified as HbA1C>7 with normal vitamin B12 greater<br />

than 200pmol/L served as the comparison group.<br />

Results: After adjusting for confounders, we found a clinically<br />

important and statistically significant association of vitamin B12 deficiency<br />

with duration of metformin use. After adjusting for confounders,<br />

we found a clinically important and statistically significant<br />

association of vitamin B12 deficiency with duration of metformin use.<br />

Among those using metformin for 1 year or more compared with<br />

those receiving metformin for less than 1 year, the adjusted odds ratio<br />

was 8.91 with a CI(4.1; 19.4),(P

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