P OSTER A BSTRACTS Conclusions: Conclusions: The results indicate that there may be a single factor underlying the responses to OHIP-14 questions in these older adults. The ohip-14 seems not to represent seven separate dimensions of oral health as originally devised. C47 Mexican-<strong>American</strong> Elder Post Hip Fracture Survival Study. D. V. Espino, 1,2 R. C. Wood, 1,2 C. C. Moore. 2,1 1. Family and Community Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX; 2. School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX. Supported By: National Institute of Health (NIH) <strong>American</strong> Federation for Aging Research (AFAR) University of Texas Health Science Center at San Antonio (UTHSCSA) As the world’s population is shifting to an older age due to advances in medical care, increased numbers of hospital visits, especially for geriatric hip fractures, are being documented. Despite the vast research conducted on hip fractures in general, little emphasis has been made on the effects of hip fractures on Mexican-<strong>American</strong>s. The Hispanic Established Populations for the Epidemiologic Study of the Elderly (H-EPESE) compiled data on risk factors for morbidity and mortality in Mexican-<strong>American</strong>s used to create a community-based survival analysis of geriatric hip fractures. The H- EPESE began in 1993 with a contingent of 3050 individuals and is currently on the seventh wave of the study. Using a Cox Model Regression Survival Analysis program, significance (p65), gender and presence or absence of Type II Diabetes Mellitus creating a drastic influence on mortality rates. Over a 7 year span after sustaining a hip fracture, a patient meeting the appropriate risk factors noted above had an approximate fifteen percent increased risk for mortality than a patient not meeting the criteria. Factors influencing the comorbidities,such as: osteoporosis in the elderly, post-menopausal hormone imbalances in women and peripheral neuropathy associated with Type II Diabetes Mellitus were investigated as contributors to the increased mortality rates. While this study does not cover the entire spectrum of comorbidities associated with increased geriatric hip fractures in the Mexican-<strong>American</strong> population, it does attempt to bridge the literature gap associated with the Mexican-<strong>American</strong> minority and create interest for expanding the literature for this subset of the population. C48 Lifetime Manic Spectrum Syndromes and All-Cause Mortality: A 26-year Follow-Up of the US National Epidemiological Catchment Area Study. C. Ramsey, 1 A. P. Spira, 1 W. W. Eaton, 1 H. B. Lee. 2,1 1. Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; 2. Psychiatry, Yale University, New Haven, CT. Background: Increasing evidence suggests a high prevalence of bipolar spectrum disorders, associated morbidity and mortality.While research supports the association between depression and mortality, the role of mania has received less attention. This analysis evaluated the association between manic spectrum syndromes and risk of mortality in the community. Methods: Participants in the prospective US National Epidemiological Catchment Area Study were classified into mutually exclusive groups based on their responses to the Diagnostic Interview Schedule items assessing mania in 1981. Those with manic spectrum syndromes (n=133; mean age: 33.8 +/- 12.6; female: 29.2%) met one of the following criteria: mania (met DSM-III criteria for a manic episode; n=36), hypomania (met all DSM-III criteria for a manic episode except the severity requirement of causing impairment or help seeking; n=42) and subsyndromal mania (had a euphoric or irritable mood for a week or more and at least one other symptom, but did not meet criteria for mania or hypomania; n=55). Participants without manic spectrum syndromes (n=13,784; mean age: 48.6 +/- 20.2; female: 53.8%) comprised the control group. Vital status through the end of follow-up in 2007 was ascertained by matching individual identifying information with the National Death Index. Manic spectrum and control groups were compared in terms of demographics, depressive symptoms, and self-rated health in 1981 using independent samples t-tests and chi-squared tests. To account for the age difference between groups, a propensity score was used. Risk of mortality was assessed using a Cox-proportional hazards model with age in 1981 as the time of entry and age at death or follow-up as the time of exit. Results: Estimated lifetime prevalence of manic spectrum syndromes was 0.98%. This group was older than the controls, had more symptoms of depression, was more likely to be married and to be Caucasian. After adjusting for these covariates in the hazard model, manic spectrum syndromes were not a significant risk factor for all-cause mortality (HR=1.3, p=0.270). Conclusions: History of manic spectrum syndromes did not increase risk of allcause mortality. Future studies should evaluate specific causes of mortality. C49 Asymptomatic Bacteriuria and Antibiotic Use in Nursing Homes. D. R. Mehr, 1 C. D. Phillips, 2 L. Adepoju, 2 D. K. Moudouni, 2 N. Stone, 4 O. Nwaiwu, 2 E. Frentzel, 3 S. Garfinkel. 3 1. Family and Community Medicine, University of Missouri, Columbia, MO; 2. Texas A&M Health Sciences Center, College Station, TX; 3. <strong>American</strong> Institutes for Research, Chapel Hill, NC; 4. Centers for Disease Control and Prevention, Atlanta, GA. Supported By: Supported by the Agency for Healthcare Research and Quality Background: Overuse of antibiotics is a longstanding concern in nursing homes. As part of a project on antibiotic stewardship, we investigated the use of antibiotics to treat asymptomatic bacteriuria (ASB) among nursing home residents with a suspected urinary tract infection (UTI). Methods: In 4 central Texas nursing homes, episodes of treatment for suspected UTI were identified from facility logs. Symptoms and resident characteristics were abstracted from residents’ records. Using a multi-level multivariate model, we evaluated resident and facility characteristics associated with antibiotic use despite the absence of symptoms and signs suggesting need to treat a UTI (criteria from Loeb, et al. Infect Control Hosp Epidemiol 2001). Results: Over 6 months, clinicians ordered antibiotics for suspected UTI 227 times among 167 residents; 89% had urine studies. Half (114) of the antibiotic prescriptions occurred in the absence of any symptoms or signs. In multivariate analyses, resident characteristics did not differentiate between treated residents with or without symptoms or signs; however, in the same model, 2 of the 4 facilities exhibited less treatment of asymptomatic residents (odd ratios and 95% confidence intervals, 0.28 [0.09,0.88] and 0.34 [0.15,0.74]). Conclusions: This research confirms frequent use of antibiotics for ASB in nursing homes. Antibiotic stewardship in nursing homes must address treatment that seems to be based solely on urine findings. Clinicians’ prescribing behavior was clearly associated with the S148 AGS 2012 ANNUAL MEETING
P OSTER A BSTRACTS nursing homes in which they practiced and may be related to, or may create, the facility’s clinical culture. C50 Hospital acquired pressure ulcers and markedly decreased survival after a hip fracture. E. I. Vidal, 1 D. C. Moreira, 6 R. S. Pinheiro, 2 F. B. Fukushima, 4 P. J. Villas Boas, 1 K. R. Camargo, 3 L. M. Almeida, 5 C. M. Coeli. 2 1. Internal Medicine Department, UNESP, Botucatu, Brazil; 2. IESC, UFJR, Rio de Janeiro, RJ, Brazil; 3. IMS, UERJ, Rio de Janeiro, RJ, Brazil; 4. Anesthesiology Department, UNESP, Botucatu, SP, Brazil; 5. Epidemiology Division, INCA, Rio de Janeiro, RJ, Brazil; 6. Social and Preventive Medicine Department, UNICAMP, Campinas, SP, Brazil. Supported By: This study was funded by the Brazilian National Council for Scientific and Technological Development (CNPq). Background: There are few data examining the association between hospital acquired pressure ulcers and survival after a hip fracture. Methods: The medical records of all patients aged 60 years and older admitted to a public university hospital in the city of Rio de Janeiro with a primary diagnosis of hip fracture between 1995 and 2000 were reviewed. Stage II or higher hospital acquired pressure ulcers were identified from medical records. Survival to hospital discharge and at 1 year was examined. Results: Among 343 patients included in the study, there were 18 (5.3%) in-hospital deaths, and 297 (86.6%) patients remained alive 1 year after surgery. A hospital acquired stage II or higher pressure ulcer was recorded in 36 (10.5%) of patients. Incident pressure ulcers were associated with markedly increased risk of reduced survival to hospital discharge (hazard ratio [HR] 4.25, 95% CI 1.35–13.36, p=0.013) and of reduced survival at 1 year after surgery (HR 4.15, 95% CI 2.14–8.06, p
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A UTHOR I NDEX Azhar, G . . . . . .
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