programma & abstracts - Nederlandse Vereniging voor Radiologie

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P <strong>programma</strong> posterpresentaties & <strong>abstracts</strong> Figuur 2: 3D-US correlation of lymph node & vascular bundle. Figuur 3: 3D-US correlation of a stellate lesion. 82 k i j k o o k o p w w w . c o n g r e s s c o m p a n y . c o m o f w w w . r a d i o l o g e n . n l
posterpresentaties P P03 BRAIN PLASTICITY IN APHASIC PATIENTS AFTER MELODIC INTONATION THERAPY ASSESSED WITH FUNCTIONAL MAGNETIC RESONANCE IMAGING (FMRI) M.A.H. Bechan 1 , W.M.E. van de Sandt-Koenderman 2 , C.P. Mendez 1 , E.G. Visch-Brink 1 , M. Smits 1 1 Erasmus Medisch Centrum, Rotterdam 2 Rijndam revalidatiecentrum, Rotterdam Purpose: Certain aphasic patients are treated with Melodic Intonation Therapy (MIT), which uses musical elements of speech to initiate language production. The purpose of this study is to visualize neuronal reorganizational processes in the brain in response to MIT using fMRI. Methods and materials: Four patients with chronic and two with acute aphasia (22-67 years; 4 males; 5 righthanded) were scanned at 3T before and after six weeks of MIT, which consisted of naming, repeating and spontaneous speech. To visualize language processing a block design task, consisting of listening to stories versus reverse speech, was used. Language performance was measured using the Sabadel story telling task. Imaging data were analyzed using Statistical Parametric Mapping 8 (London, UK). After preprocessing individual statistical t-contrast maps were calculated for pre- and post-therapy datasets. Lateralization indices (LI) were calculated using the number of significantly (p
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