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Activity Report 2010 - CNRS

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OVERVIEW<br />

Tetiana AKSENOVA - A leading expert<br />

involved in the unique world class<br />

program CLINATEC ® .<br />

Previously engineerresearcher<br />

at INSERM,<br />

U318 CHU Grenoble<br />

(from 2002 to 2007),<br />

Tetiana AKSENOVA, 53,<br />

came back to Grenoble<br />

thanks to a full time<br />

Chair of Excellence<br />

granted through the<br />

Nanosciences Foundation’s 2008 Call.<br />

On leave from Ukrainian Academy of<br />

Sciences, and presently at Léti, Tetiana is<br />

also the co-founder of PNN-Soft. Her<br />

group leader proposed CEA to hire<br />

Tetiana full time at the end of the<br />

Nanosciences Foundation’s support.<br />

The procedure of adaptive<br />

calibration is aimed to the fasten BCI<br />

system installation and recalibration. In<br />

<strong>2010</strong> the principle solution for the<br />

adaptive BCI calibration system was<br />

proposed, based on the innovative<br />

recursive algorithm.<br />

There is a constant effort on the<br />

optimization of algorithms. To move<br />

toward multiple degrees of freedom in<br />

humans and in order to improve the BCI<br />

performance the algorithm of fast signal<br />

decomposition were proposed (patent in<br />

preparation).<br />

Leading expert in the field of machine<br />

learning and real time signal processing,<br />

Tetiana AKSENOVA invented several<br />

innovative approaches for signal<br />

processing, classification and modelling<br />

that can be used for Brain Computer<br />

Interface design. She made a crucial<br />

improvement in the theoretical study and<br />

practical application of GMDH-type<br />

(Group Method of Data Handling) neural<br />

networks, effective self learning approach<br />

for the regression analysis which is used<br />

as a basis for self learning procedure of<br />

Brain Computer Interface (BCI).<br />

Her activity at CLINATEC ® overlaps with<br />

the project Neurolink which aims at<br />

improving the stability and the quality of<br />

electrical interface between neural<br />

network and nanostructured electrodes<br />

using multiwall carbon nanotubes.<br />

The challenge of the project is to design<br />

fully autonomous self-paced systems for<br />

continuous long term monitoring of<br />

neuronal activity functioning in natural<br />

noisy environment. Major achievements<br />

have already been obtained:<br />

Functional self-paced BCI with<br />

one degree of freedom in freely moving<br />

animals (rodents) was achieved during<br />

the first year of the project. It includes<br />

the development of basic methods and<br />

algorithms (offline and online), software<br />

implementation on MatLab and their<br />

incorporation into the BCI platform. (A<br />

patent has been submitted in <strong>2010</strong>.)<br />

The second year concerned<br />

preclinical studies in animals. Self paced<br />

1D BCI system demonstrated perfect<br />

robustness and high quality of prediction:<br />

the 8 month- long experiment with one<br />

animal validated the robustness of<br />

algorithms. The experiments to study of<br />

Subject-to-Subject variability with<br />

several animals are in progress.<br />

6

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