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Principles of cell signaling - UT Southwestern

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39057_ch14_<strong>cell</strong>bio.qxd 8/28/06 5:11 PM Page 642<br />

14.29 The Wnt pathway regulates <strong>cell</strong> fate during<br />

development and other processes in<br />

the adult<br />

Review<br />

Logan, C. Y. and Nusse, R., 2004. The WNT<br />

<strong>signaling</strong> pathway in development and<br />

disease. Annu. Rev. Cell. Dev. Biol. v. 20, p.<br />

781–810.<br />

Tolwinski, N. S., Wieschaus, E., 2004.<br />

Rethinking WNT <strong>signaling</strong>. Trends Genet.<br />

v. 20 p. 177–81.<br />

14.30 Diverse <strong>signaling</strong> mechanisms are regulated<br />

by protein tyrosine kinases<br />

Review<br />

Birge, R. B., Knudsen, B. S., Besser, D., and<br />

Hanafusa, H., 1996. SH2 and SH3-containing<br />

adaptor proteins: redundant or<br />

independent mediators <strong>of</strong> intra<strong>cell</strong>ular<br />

signal transduction. Genes Cells v. 1 p.<br />

595–613.<br />

Blume-Jensen, P. and Hunter, T., 2001.<br />

Oncogenic kinase signalling. Nature v.<br />

411 p. 355–365.<br />

Cohen, P., 2002. Protein kinases—the major<br />

drug targets <strong>of</strong> the twenty-first century?<br />

Nat. Rev. Drug Discov. v. 1 p. 309–315.<br />

Pawson, T. and Nash, P., 2003. Assembly <strong>of</strong><br />

<strong>cell</strong> regulatory systems through protein<br />

interaction domains. Science v. 300 p.<br />

445–452.<br />

Tallquist, M. and Kazlauskas, A., 2004. PDGF<br />

<strong>signaling</strong> in <strong>cell</strong>s and mice. Cytokine<br />

Growth Factor Rev. v. 15 p. 205–213.<br />

Taniguchi, C. M., Emanuelli, B., and Kahn, C.<br />

R., 2006. Critical nodes in signalling<br />

pathways: insights into insulin action.<br />

Nat. Rev. Mol. Cell Biol. v. 7, p. 85–96.<br />

14.31 Src family protein kinases cooperate with<br />

receptor protein tyrosine kinases<br />

Review<br />

Boggon, T. J. and Eck, M. J., 2004. Structure<br />

and regulation <strong>of</strong> Src family kinases.<br />

Oncogene v. 23 p. 7918–7927.<br />

Frame, M. C., 2004. Newest findings on the<br />

oldest oncogene; how activated src does<br />

it. J. Cell Sci. v. 117 p. 989–998.<br />

Research<br />

Cowan-Jacob, S. W., Frendrich, G., Manley, P.<br />

W., Jahnke, W., Fabbro, D.,<br />

Liebetanz, J., Meyer, T. 2005. The<br />

crystal structure <strong>of</strong> a c-Src complex in<br />

an active conformation suggests possible<br />

steps in c-Src activation Structure<br />

v. 13 p. 861–871.<br />

Xu, W., Harrison, S. C., and Eck, M. J., 1997.<br />

Three-dimensional structure <strong>of</strong> the tyro-<br />

sine kinase c-Src. Nature v. 385 p.<br />

595–602.<br />

14.32 MAPKs are central to many <strong>signaling</strong><br />

pathways<br />

Review<br />

Chen, Z., Gibson, T. B., Robinson, F.,<br />

Silvestro, L., Pearson, G., Xu, B., Wright,<br />

A., Vanderbilt, C., and Cobb, M. H., 2001.<br />

MAP kinases. Chem. Rev. v. 101 p.<br />

2449–2476.<br />

Lewis, T. S., Shapiro, P. S., and Ahn, N. G.,<br />

1998. Signal transduction through MAP<br />

kinase cascades. Adv. Cancer Res. v. 74 p.<br />

49–139.<br />

Morrison, D. K. and Davis, R. J., 2003.<br />

Regulation <strong>of</strong> MAP kinase <strong>signaling</strong> modules<br />

by scaffold proteins in mammals.<br />

Annu. Rev. Cell Dev. Biol. v. 19 p. 91–118.<br />

Sharrocks, A. D., Yang, S. H., and Galanis, A.,<br />

2000. Docking domains and substratespecificity<br />

determination for MAP kinases.<br />

Trends Biochem. Sci. v. 25 p.<br />

448–453.<br />

Research<br />

Anderson, N. G., Maller, J. L., Tonks, N. K.,<br />

and Sturgill, T. W., 1990. Requirement<br />

for integration <strong>of</strong> signals from two distinct<br />

phosphorylation pathways for activation<br />

<strong>of</strong> MAP kinase. Nature v. 343 p.<br />

651–653.<br />

14.33 Cyclin-dependent protein kinases control<br />

the <strong>cell</strong> cycle<br />

Review<br />

Dorée, M. and Hunt, T., 2002. From Cdc2 to<br />

Cdk1: when did the <strong>cell</strong> cycle kinase join<br />

its cyclin partner? J. Cell Sci. v. 115 p.<br />

2461–2464.<br />

Hartwell, L. H., 1991. Twenty-five years <strong>of</strong><br />

<strong>cell</strong> cycle genetics. Genetics v. 129 p.<br />

975–980.<br />

Neely, K. E. and Piwnica-Worms, H., 2003.<br />

Cdc25A regulation: to destroy or not to<br />

destroy—is that the only question? Cell<br />

Cycle v. 2 p. 455–457.<br />

Nurse, P., 2000. A long twentieth century <strong>of</strong><br />

the <strong>cell</strong> cycle and beyond. Cell v. 100 p.<br />

71–78.<br />

Research<br />

Pavletich, N. P., 1999. Mechanisms <strong>of</strong> cyclindependent<br />

kinase regulation: structures<br />

<strong>of</strong> Cdks, their cyclin activators, and Cip<br />

and INK4 inhibitors. J. Mol. Biol. v. 287 p.<br />

821–828.<br />

Russo, A. A., Jeffrey, P. D., and Pavletich, N.<br />

P., 1996. Structural basis <strong>of</strong> cyclin-dependent<br />

kinase activation by phosphorylation.<br />

Nat. Struct. Biol. v. 3 p. 696–700.<br />

642 CHAPTER 14 <strong>Principles</strong> <strong>of</strong> <strong>cell</strong> <strong>signaling</strong>

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