25.11.2014 Views

Biostatistics

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

6.10 CONFIDENCE INTERVAL FOR THE RATIO OF THE VARIANCES OF TWO NORMALLY DISTRIBUTED POPULATIONS 199<br />

f (x)<br />

1.0<br />

0.8<br />

0.6<br />

0.4<br />

(10; ∞)<br />

(10; 50)<br />

(10; 10)<br />

(10; 4)<br />

0.2<br />

0.0<br />

0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0<br />

F<br />

FIGURE 6.10.1 The F distribution for various degrees of freedom.<br />

(From Documenta Geigy, Scientific Tables, Seventh Edition, 1970. Courtesy of Ciba-Geigy Limited, Basel,<br />

Switzerland.)<br />

examined. If the confidence interval for the ratio of two population variances includes 1, we<br />

conclude that the two population variances may, in fact, be equal. Again, since this is a form<br />

of inference, we must rely on some sampling distribution, and this time the distribution of<br />

s 2 1 1 =s2 = s<br />

2<br />

2 =s2 2 is utilized provided certain assumptions are met. The assumptions are<br />

that s 2 1 and s2 2 are computed from independent samples of size n 1 and n 2 respectively, drawn<br />

from two normally distributed populations. We use s 2 1 to designate the larger of the two<br />

sample variances.<br />

The F Distribution If the assumptions are met, s 2 1 1 =s2 = s<br />

2<br />

2 =s2 2 follows a<br />

distribution known as the F distribution. We defer a more complete discussion of this<br />

distribution until chapter 8, but note that this distribution depends on two-degrees-offreedom<br />

values, one corresponding to the value of n 1 1 used in computing s 2 1 and the<br />

other corresponding to the value of n 2 1 used in computing s 2 2 . These are usually referred<br />

to as the numerator degrees of freedom and the denominator degrees of freedom.<br />

Figure 6.10.1 shows some F distributions for several numerator and denominator<br />

degrees-of-freedom combinations. Appendix Table G contains, for specified combinations<br />

of degrees of freedom and values of a; F values to the right of which lies a=2 of the area<br />

under the curve of F.<br />

A Confidence Interval for s 2 1 =s2 2<br />

To find the 100ð1 aÞ percent confidence<br />

interval for s 2 1 =s2 2 , we begin with the expression<br />

F a=2 < s2 1 =s2 1<br />

s 2 2 =s2 2<br />

< F 1 ða=2Þ<br />

where F a=2 and F 1 ða=2Þ<br />

are the values from the F table to the left and right of which,<br />

respectively, lies a=2 of the area under the curve. The middle term of this expression may<br />

be rewritten so that the entire expression is<br />

F a=2 < s2 1<br />

s 2 s2 2<br />

2<br />

s 2 1<br />

< F 1 ða=2Þ

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!