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Biostatistics

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762 CHAPTER 14 SURVIVAL ANALYSIS<br />

Subject Time a (Years) Status b Subject Time a (Years) Status b (Continued)<br />

11 2 mtc 38 9 alive<br />

12 2 mtc 39 10 alive<br />

13 2 alive 40 11 mtc<br />

14 2 alive 41 11 doc<br />

15 3 mtc 42 12 mtc<br />

16 3 mtc 43 12 doc<br />

17 3 alive 44 13 mtc<br />

18 4 mtc 45 14 alive<br />

19 4 alive 46 15 alive<br />

20 4 alive 47 16 mtc<br />

21 4 alive 48 16 alive<br />

22 5 alive 49 16 alive<br />

23 5 alive 50 16 alive<br />

24 5 alive 51 17 doc<br />

25 5 alive 52 18 mtc<br />

26 6 alive 53 19 alive<br />

27 6 alive<br />

a Time is number of years after surgery.<br />

b doc ¼ dead of other causes; mtc ¼ dead of medullary thyroid cancer.<br />

source: Data provided courtesy of Dr. Massimo E. Dottorini.<br />

14.3.2 Banerji et al. (A-3) followed non–insulin-dependent diabetes mellitus (NIDDM) patients from onset<br />

of their original hyperglycemia and the inception of their near–normoglycemic remission following<br />

treatment. Subjects were black men and women with a mean age of 45.4 years and a standard<br />

deviation of 10.4. The following table shows the relapse/remission experience of 62 subjects.<br />

Calculate the survival function using the Kaplan–Meier procedure and plot the survival curve.<br />

Total<br />

Duration of<br />

Remission<br />

(Months)<br />

Remission<br />

Status a<br />

Total<br />

Duration of<br />

Remission<br />

(Months)<br />

Remission<br />

Status a<br />

Total<br />

Duration of<br />

Remission<br />

(Months)<br />

Remission<br />

Status a<br />

3 1 8 2 26 1<br />

3 2 9 2 27 1<br />

3 1 10 1 28 2<br />

3 1 10 1 29 1<br />

3 1 11 2 31 2<br />

4 1 13 1 31 1<br />

4 1 16 1 33 2<br />

4 1 16 2 39 2<br />

5 1 17 2 41 1<br />

5 1 18 2 44 1<br />

5 1 20 1 46 1<br />

5 1 22 1 46 2<br />

5 1 22 2 48 1<br />

5 1 22 2 48 2

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